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Progesterone administration for luteal phase deficiency in human reproduction: an old or new issue?

Overview of attention for article published in Journal of Ovarian Research, November 2015
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  • Good Attention Score compared to outputs of the same age (72nd percentile)
  • High Attention Score compared to outputs of the same age and source (90th percentile)

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1 X user
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1 Facebook page
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1 Wikipedia page

Citations

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85 Mendeley
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Title
Progesterone administration for luteal phase deficiency in human reproduction: an old or new issue?
Published in
Journal of Ovarian Research, November 2015
DOI 10.1186/s13048-015-0205-8
Pubmed ID
Authors

Stefano Palomba, Susanna Santagni, Giovanni Battista La Sala

Abstract

Luteal phase deficiency (LPD) is described as a condition of insufficient progesterone exposure to maintain a regular secretory endometrium and allow for normal embryo implantation and growth. Recently, scientific focus is turning to understand the physiology of implantation, in particular the several molecular markers of endometrial competence, through the recent transcriptomic approaches and microarray technology. In spite of the wide availability of clinical and instrumental methods for assessing endometrial competence, reproducible and reliable diagnostic tests for LPD are currently lacking, so no type-IA evidence has been proposed by the main scientific societies for assessing endometrial competence in infertile couples. Nevertheless, LPD is a very common condition that may occur during a series of clinical conditions, and during controlled ovarian stimulation (COS) and hyperstimulation (COH) programs. In many cases, the correct approach to treat LPD is the identification and correction of any underlying condition while, in case of no underlying dysfunction, the treatment becomes empiric. To date, no direct data is available regarding the efficacy of luteal phase support for improving fertility in spontaneous cycles or in non-gonadotropin induced ovulatory cycles. On the contrary, in gonadotropin in vitro fertilization (IVF) and non-IVF cycles, LPD is always present and progesterone exerts a significant positive effect on reproductive outcomes. The scientific debate still remains open regarding progesterone administration protocols, specially on routes of administration, dose and timing and the potential association with other drugs, and further research is still needed.

X Demographics

X Demographics

The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 85 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Ghana 1 1%
Unknown 84 99%

Demographic breakdown

Readers by professional status Count As %
Student > Master 14 16%
Other 10 12%
Student > Bachelor 10 12%
Researcher 8 9%
Student > Doctoral Student 6 7%
Other 16 19%
Unknown 21 25%
Readers by discipline Count As %
Medicine and Dentistry 37 44%
Biochemistry, Genetics and Molecular Biology 7 8%
Nursing and Health Professions 7 8%
Agricultural and Biological Sciences 4 5%
Social Sciences 3 4%
Other 6 7%
Unknown 21 25%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 4. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 03 May 2020.
All research outputs
#6,806,974
of 22,854,458 outputs
Outputs from Journal of Ovarian Research
#88
of 590 outputs
Outputs of similar age
#105,631
of 386,564 outputs
Outputs of similar age from Journal of Ovarian Research
#1
of 11 outputs
Altmetric has tracked 22,854,458 research outputs across all sources so far. This one has received more attention than most of these and is in the 69th percentile.
So far Altmetric has tracked 590 research outputs from this source. They receive a mean Attention Score of 3.2. This one has done well, scoring higher than 84% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 386,564 tracked outputs that were published within six weeks on either side of this one in any source. This one has gotten more attention than average, scoring higher than 72% of its contemporaries.
We're also able to compare this research output to 11 others from the same source and published within six weeks on either side of this one. This one has done particularly well, scoring higher than 90% of its contemporaries.