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Reproductive and genital health and risk of cervical human papillomavirus infection: results from the Ludwig-McGill cohort study

Overview of attention for article published in BMC Infectious Diseases, March 2016
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Title
Reproductive and genital health and risk of cervical human papillomavirus infection: results from the Ludwig-McGill cohort study
Published in
BMC Infectious Diseases, March 2016
DOI 10.1186/s12879-016-1446-x
Pubmed ID
Authors

Eileen Shaw, Agnihotram V. Ramanakumar, Mariam El-Zein, Flavia R. Silva, Lenice Galan, Maria L. Baggio, Luisa L. Villa, Eduardo L. Franco, for the Ludwig-McGill Cohort Study

Abstract

There are inconsistencies in the literature on reproductive and genital health determinants of human papillomavirus (HPV) infection, the primary cause of cervical cancer. We examined these factors in the Ludwig-McGill Cohort Study, a longitudinal, repeated-measurements investigation on the natural history of HPV infection. We analyzed a cohort subset of 1867 women with one complete year of follow-up. We calculated odds ratios (OR) and 95 % confidence intervals (CI) for reproductive and genital health characteristics from questionnaire and laboratory data in relation to 1-year period prevalence of HPV infection. Two outcomes were measured; the first based on phylogenetic grouping of HPV types based on tissue tropism and oncogenicity (Alphapapillomavirus Subgenus 1: species 1, 8, 10 and 13; Subgenus 2: species 5, 6, 7, 9, 11; Subgenus 3: species 3, 4 and 14) and the second based on transient or persistent HPV infections. Lifetime (Subgenus 3 OR = 2.00, CI: 1.23-3.24) and current (Subgenus 3 OR = 2.00, CI: 1.15-3.47) condom use and use of contraceptive injections (Subgenus 1 OR = 1.96, CI: 1.22-3.16, Subgenus 2 OR = 1.34, CI: 1.00-1.79) were associated with increased risk of HPV infection. Intrauterine device use was protective (Subgenus 1 OR = 0.48, CI: 0.30-0.75, Subgenus 2 OR = 0.78, CI: 0.62-0.98). These factors were not associated with persistence of HPV infection. Tampon use, previous gynecologic infections and cervical inflammation were associated with an overall increased risk of HPV infection. Cervical HPV infection was associated with reproductive and genital health factors. Further studies are necessary to confirm the low to moderate associations observed.

Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 97 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Canada 1 1%
Unknown 96 99%

Demographic breakdown

Readers by professional status Count As %
Researcher 17 18%
Student > Master 11 11%
Student > Bachelor 11 11%
Student > Ph. D. Student 10 10%
Professor 7 7%
Other 21 22%
Unknown 20 21%
Readers by discipline Count As %
Medicine and Dentistry 32 33%
Nursing and Health Professions 9 9%
Biochemistry, Genetics and Molecular Biology 8 8%
Agricultural and Biological Sciences 4 4%
Social Sciences 3 3%
Other 15 15%
Unknown 26 27%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 09 March 2016.
All research outputs
#20,885,314
of 23,507,405 outputs
Outputs from BMC Infectious Diseases
#6,600
of 7,830 outputs
Outputs of similar age
#254,682
of 300,947 outputs
Outputs of similar age from BMC Infectious Diseases
#102
of 111 outputs
Altmetric has tracked 23,507,405 research outputs across all sources so far. This one is in the 1st percentile – i.e., 1% of other outputs scored the same or lower than it.
So far Altmetric has tracked 7,830 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 10.4. This one is in the 1st percentile – i.e., 1% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 300,947 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 1st percentile – i.e., 1% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 111 others from the same source and published within six weeks on either side of this one. This one is in the 1st percentile – i.e., 1% of its contemporaries scored the same or lower than it.