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CoINcIDE: A framework for discovery of patient subtypes across multiple datasets

Overview of attention for article published in Genome Medicine, March 2016
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About this Attention Score

  • In the top 25% of all research outputs scored by Altmetric
  • High Attention Score compared to outputs of the same age (86th percentile)
  • Average Attention Score compared to outputs of the same age and source

Mentioned by

twitter
12 X users
patent
2 patents
facebook
1 Facebook page

Citations

dimensions_citation
28 Dimensions

Readers on

mendeley
65 Mendeley
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2 CiteULike
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Title
CoINcIDE: A framework for discovery of patient subtypes across multiple datasets
Published in
Genome Medicine, March 2016
DOI 10.1186/s13073-016-0281-4
Pubmed ID
Authors

Catherine R. Planey, Olivier Gevaert

Abstract

Patient disease subtypes have the potential to transform personalized medicine. However, many patient subtypes derived from unsupervised clustering analyses on high-dimensional datasets are not replicable across multiple datasets, limiting their clinical utility. We present CoINcIDE, a novel methodological framework for the discovery of patient subtypes across multiple datasets that requires no between-dataset transformations. We also present a high-quality database collection, curatedBreastData, with over 2,500 breast cancer gene expression samples. We use CoINcIDE to discover novel breast and ovarian cancer subtypes with prognostic significance and novel hypothesized ovarian therapeutic targets across multiple datasets. CoINcIDE and curatedBreastData are available as R packages.

X Demographics

X Demographics

The data shown below were collected from the profiles of 12 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 65 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United Kingdom 1 2%
United States 1 2%
Unknown 63 97%

Demographic breakdown

Readers by professional status Count As %
Researcher 18 28%
Student > Ph. D. Student 13 20%
Student > Master 7 11%
Other 4 6%
Student > Postgraduate 3 5%
Other 11 17%
Unknown 9 14%
Readers by discipline Count As %
Agricultural and Biological Sciences 17 26%
Biochemistry, Genetics and Molecular Biology 10 15%
Medicine and Dentistry 10 15%
Computer Science 7 11%
Engineering 5 8%
Other 6 9%
Unknown 10 15%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 13. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 04 November 2020.
All research outputs
#2,799,028
of 25,402,528 outputs
Outputs from Genome Medicine
#641
of 1,587 outputs
Outputs of similar age
#43,354
of 314,772 outputs
Outputs of similar age from Genome Medicine
#24
of 38 outputs
Altmetric has tracked 25,402,528 research outputs across all sources so far. Compared to these this one has done well and is in the 88th percentile: it's in the top 25% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 1,587 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 26.8. This one has gotten more attention than average, scoring higher than 59% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 314,772 tracked outputs that were published within six weeks on either side of this one in any source. This one has done well, scoring higher than 86% of its contemporaries.
We're also able to compare this research output to 38 others from the same source and published within six weeks on either side of this one. This one is in the 39th percentile – i.e., 39% of its contemporaries scored the same or lower than it.