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RETRACTED ARTICLE: High doses of garlic extract significantly attenuated the ratio of serum LDL to HDL level in rat-fed with hypercholesterolemia diet

Overview of attention for article published in Diagnostic Pathology, June 2015
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Title
RETRACTED ARTICLE: High doses of garlic extract significantly attenuated the ratio of serum LDL to HDL level in rat-fed with hypercholesterolemia diet
Published in
Diagnostic Pathology, June 2015
DOI 10.1186/s13000-015-0322-0
Pubmed ID
Authors

Tahereh Ebrahimi, Behnoosh Behdad, Maryam Agha Abbasi, Rahman Ghaffarzadegan Rabati, Amir Farshid Fayyaz, Vahid Behnod, Ali Asgari

Abstract

Hypercholesterolemia is associated with an increased risk of heart disease. In this study, we investigated the antihyperlipidemic effects of garlic (Allium sativum L.) in rat models of hypercholesterolemic. Wistar male rats were randomly divided into 4 diet groups with garlic supplementation. Male Wistar rats were fed by standard pellet diet (group I), standard diet supplemented with 4 % garlic (group II), lipogenic diet (containing sunflower oil, cholesterol and ethanol) equivalent to 200 mg raw garlic/kg body weight (raw) (group III) and lipogenic diet equivalent to 400 mg raw garlic/kg body weight (raw) (group IV). Rats fed 400 g/kg garlic extract(GE), had a significantly lower concentration of serum low-density lipoprotein cholesterol (LDL-C) cholesterol and elevated HDL -C cholesterol at day 28 (P < 0.05).In addition,serum levels of LDL-C was lower in the III and IV group than those in the IV group (P < 0.001 for each). However, cholesterol efflux capacity was positively correlated with HDL cholesterol concentration (P < 0 · 0001). It was also directly correlated with garlic supplementation (P < 0 · 0001). Together Taken, the results are clearly indicative of the beneficial effects of garlic in reducing lateral side effects of hyperlipidemia. Our data demonstrate that GE has protective effects on HDL in rats with high LDL intake. Therefore, it could be used to remedy hypercholesterolemia with help reduce risk of coronary heart disease The virtual slide(s) for this article can be found here: http://www.diagnosticpathology.diagnomx.eu/vs/1834155749171141.

Twitter Demographics

The data shown below were collected from the profile of 1 tweeter who shared this research output. Click here to find out more about how the information was compiled.

Mendeley readers

The data shown below were compiled from readership statistics for 39 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
India 1 3%
Unknown 38 97%

Demographic breakdown

Readers by professional status Count As %
Student > Bachelor 14 36%
Student > Doctoral Student 4 10%
Other 4 10%
Lecturer 3 8%
Student > Ph. D. Student 1 3%
Other 3 8%
Unknown 10 26%
Readers by discipline Count As %
Medicine and Dentistry 10 26%
Pharmacology, Toxicology and Pharmaceutical Science 6 15%
Nursing and Health Professions 3 8%
Sports and Recreations 3 8%
Computer Science 2 5%
Other 4 10%
Unknown 11 28%

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 17 April 2019.
All research outputs
#11,614,039
of 14,656,415 outputs
Outputs from Diagnostic Pathology
#544
of 884 outputs
Outputs of similar age
#184,594
of 265,853 outputs
Outputs of similar age from Diagnostic Pathology
#17
of 19 outputs
Altmetric has tracked 14,656,415 research outputs across all sources so far. This one is in the 11th percentile – i.e., 11% of other outputs scored the same or lower than it.
So far Altmetric has tracked 884 research outputs from this source. They receive a mean Attention Score of 2.2. This one is in the 18th percentile – i.e., 18% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 265,853 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 17th percentile – i.e., 17% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 19 others from the same source and published within six weeks on either side of this one. This one is in the 10th percentile – i.e., 10% of its contemporaries scored the same or lower than it.