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Study of Leishmania pathogenesis in mice: experimental considerations

Overview of attention for article published in Parasites & Vectors, March 2016
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3 X users

Citations

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285 Mendeley
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Title
Study of Leishmania pathogenesis in mice: experimental considerations
Published in
Parasites & Vectors, March 2016
DOI 10.1186/s13071-016-1413-9
Pubmed ID
Authors

Corinne Loeuillet, Anne-Laure Bañuls, Mallorie Hide

Abstract

Although leishmaniases are endemic in 98 countries, they are still considered neglected tropical diseases. Leishmaniases are characterized by the emergence of new virulent and asymptomatic strains of Leishmania spp. and, as a consequence, by a very diverse clinical spectrum. To fight more efficiently these parasites, the mechanisms of host defense and of parasite virulence need to be thoroughly investigated. To this aim, animal models are widely used. However, the results obtained with these models are influenced by several experimental parameters, such as the mouse genetic background, parasite genotype, inoculation route/infection site, parasite dose and phlebotome saliva. In this review, we propose an update on their influence in the two main clinical forms of the disease: cutaneous and visceral leishmaniases.

X Demographics

X Demographics

The data shown below were collected from the profiles of 3 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 285 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Sri Lanka 1 <1%
France 1 <1%
Unknown 283 99%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 45 16%
Researcher 39 14%
Student > Master 39 14%
Student > Bachelor 35 12%
Student > Doctoral Student 20 7%
Other 47 16%
Unknown 60 21%
Readers by discipline Count As %
Agricultural and Biological Sciences 47 16%
Immunology and Microbiology 44 15%
Biochemistry, Genetics and Molecular Biology 35 12%
Medicine and Dentistry 25 9%
Pharmacology, Toxicology and Pharmaceutical Science 18 6%
Other 34 12%
Unknown 82 29%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 15 March 2016.
All research outputs
#15,364,458
of 22,856,968 outputs
Outputs from Parasites & Vectors
#3,385
of 5,470 outputs
Outputs of similar age
#178,381
of 299,532 outputs
Outputs of similar age from Parasites & Vectors
#119
of 180 outputs
Altmetric has tracked 22,856,968 research outputs across all sources so far. This one is in the 22nd percentile – i.e., 22% of other outputs scored the same or lower than it.
So far Altmetric has tracked 5,470 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 5.7. This one is in the 30th percentile – i.e., 30% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 299,532 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 31st percentile – i.e., 31% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 180 others from the same source and published within six weeks on either side of this one. This one is in the 26th percentile – i.e., 26% of its contemporaries scored the same or lower than it.