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Is caffeine intake a risk factor leading to infertility? A protocol of an epidemiological systematic review of controlled clinical studies

Overview of attention for article published in Systematic Reviews, March 2016
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  • In the top 25% of all research outputs scored by Altmetric
  • High Attention Score compared to outputs of the same age (83rd percentile)
  • Good Attention Score compared to outputs of the same age and source (71st percentile)

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10 X users
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2 Facebook pages

Citations

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6 Dimensions

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27 Mendeley
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Title
Is caffeine intake a risk factor leading to infertility? A protocol of an epidemiological systematic review of controlled clinical studies
Published in
Systematic Reviews, March 2016
DOI 10.1186/s13643-016-0221-9
Pubmed ID
Authors

Huijuan Cao, Jun Ren, Xue Feng, Guoyan Yang, Jianping Liu

Abstract

Previous studies showed that high dose of caffeine intake may induce some specific human reproductive system diseases, even lead to infertility. In consideration of the high consumption of caffeine according to the latest population-based survey, this review is aimed to systematically review the evidence from all controlled clinical studies of caffeine intake for infertility. Relevant randomized/quasi-randomized controlled trials, non-randomized clinical studies, cohort studies, and case-control studies will be included in this review. Participants will be either those without a history of infertility who are willing to have a baby (for prospective studies) or infertile patients with confirmed diagnosis (for retrospective studies). Caffeine or caffeine-containing beverage will be observed as the exposure factor. The key outcome will be the diagnosis of infertility in participants. All relevant published/unpublished or ongoing studies will be searched from seven databases and four online systems until December 2015. Two authors will screen the literatures and extract the data independently. Methodological quality of the included studies will be assessed by two authors according to either Risk of Bias Assessment or Newcastle-Ottawa Scale. We will use R software to analyze the data. Dose of caffeine will be quantified on a daily basis, and relative risk with their 95 % confidence interval will be measured. If data permit, meta-analysis and dose-response analysis will be conducted. Summary of findings tables will be generated using Guideline Development Tool online. PROSPERO CRD42015015714.

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X Demographics

The data shown below were collected from the profiles of 10 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 27 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 27 100%

Demographic breakdown

Readers by professional status Count As %
Student > Bachelor 6 22%
Student > Master 5 19%
Student > Ph. D. Student 3 11%
Professor 2 7%
Professor > Associate Professor 2 7%
Other 4 15%
Unknown 5 19%
Readers by discipline Count As %
Medicine and Dentistry 11 41%
Nursing and Health Professions 3 11%
Engineering 2 7%
Pharmacology, Toxicology and Pharmaceutical Science 1 4%
Unspecified 1 4%
Other 3 11%
Unknown 6 22%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 9. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 25 March 2016.
All research outputs
#3,649,077
of 22,856,968 outputs
Outputs from Systematic Reviews
#690
of 1,999 outputs
Outputs of similar age
#63,400
of 393,628 outputs
Outputs of similar age from Systematic Reviews
#22
of 76 outputs
Altmetric has tracked 22,856,968 research outputs across all sources so far. Compared to these this one has done well and is in the 84th percentile: it's in the top 25% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 1,999 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 12.7. This one has gotten more attention than average, scoring higher than 65% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 393,628 tracked outputs that were published within six weeks on either side of this one in any source. This one has done well, scoring higher than 83% of its contemporaries.
We're also able to compare this research output to 76 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 71% of its contemporaries.