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Elevated serum alpha-fetoprotein in poorly differentiated adenocarcinoma with neuroendocrine differentiation of the ascending colon: a case report.

Overview of attention for article published in World Journal of Surgical Oncology, January 2016
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1 tweeter

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Title
Elevated serum alpha-fetoprotein in poorly differentiated adenocarcinoma with neuroendocrine differentiation of the ascending colon: a case report.
Published in
World Journal of Surgical Oncology, January 2016
DOI 10.1186/s12957-016-0838-0
Pubmed ID
Authors

Lin, Hung-Hsin, Chang, Chia-Chu, Yang, Shung-Haur, Chang, Shih-Ching, Chen, Wei-Shone, Liang, Wen-Yih, Lin, Jen-Kou, Jiang, Jeng-Kai

Abstract

Colorectal cancer (CRC) is the most common form of cancer and the third leading cause of death in Taiwan. Serum alpha-fetoprotein (AFP) has been extensively used as a biomarker for hepatocellular carcinoma (HCC) and yolk sac tumors. This case report presents a 90-year-old woman with right abdominal pain and poor appetite for 1 week. The computed tomography (CT) showed wall thickening in the proximal ascending colon with ruptured appendicitis. Preoperative serum AFP was high. There was no definite liver metastasis or other abnormal findings in the hepatobiliary systems. After initial empirical antibiotic treatment, we performed laparoscopic right hemicolectomy. The pathological assessment was poorly differentiated adenocarcinoma with neuroendocrine differentiation in the ascending colon. The tumor cells did not produce AFP. Amazingly, the follow-up serum AFP level 1 month after the surgery declined to normal range. The patient had an uneventful course after the surgery and was free of recurrence or metastasis within 5 months of follow-up. AFP may be a useful tumor marker in poorly differentiated colorectal cancer with neuroendocrine component patients and a prediction of early treatment response.

Twitter Demographics

The data shown below were collected from the profile of 1 tweeter who shared this research output. Click here to find out more about how the information was compiled.

Mendeley readers

The data shown below were compiled from readership statistics for 26 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 26 100%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 6 23%
Student > Master 4 15%
Other 2 8%
Student > Doctoral Student 2 8%
Student > Bachelor 1 4%
Other 1 4%
Unknown 10 38%
Readers by discipline Count As %
Medicine and Dentistry 11 42%
Biochemistry, Genetics and Molecular Biology 1 4%
Agricultural and Biological Sciences 1 4%
Nursing and Health Professions 1 4%
Chemistry 1 4%
Other 1 4%
Unknown 10 38%

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 16 March 2016.
All research outputs
#6,405,647
of 7,401,456 outputs
Outputs from World Journal of Surgical Oncology
#1,030
of 1,184 outputs
Outputs of similar age
#233,368
of 275,610 outputs
Outputs of similar age from World Journal of Surgical Oncology
#32
of 50 outputs
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