Title |
Association between inhaled nitric oxide treatment and long-term pulmonary function in survivors of acute respiratory distress syndrome
|
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Published in |
Critical Care, March 2012
|
DOI | 10.1186/cc11215 |
Pubmed ID | |
Authors |
R Phillip Dellinger, Stephen W Trzeciak, Gerard J Criner, Janice L Zimmerman, Robert W Taylor, Helen Usansky, Joseph Young, Brahm Goldstein |
Abstract |
Assessment of treatments for acute respiratory distress syndrome (ARDS) has focused on short-term outcomes (for example, mortality); little information exists regarding long-term effects of ARDS treatment. Survivors of ARDS episodes may have long-term obstructive/restrictive pulmonary abnormalities and pulmonary gas exchange impairment. A 2004 prospective randomized placebo-controlled trial assessed the efficacy and safety of inhaled nitric oxide (iNO) in patients with non-septic ARDS; the primary endpoint was days alive and off assisted breathing. This analysis examined potential effects of iNO or placebo on pulmonary function six months post-treatment in ARDS survivors from that original study. |
X Demographics
Geographical breakdown
Country | Count | As % |
---|---|---|
Unknown | 2 | 100% |
Demographic breakdown
Type | Count | As % |
---|---|---|
Members of the public | 1 | 50% |
Practitioners (doctors, other healthcare professionals) | 1 | 50% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
Brazil | 2 | 2% |
Greece | 1 | 1% |
Canada | 1 | 1% |
France | 1 | 1% |
Unknown | 81 | 94% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Researcher | 12 | 14% |
Student > Master | 10 | 12% |
Other | 9 | 10% |
Student > Postgraduate | 6 | 7% |
Student > Bachelor | 6 | 7% |
Other | 18 | 21% |
Unknown | 25 | 29% |
Readers by discipline | Count | As % |
---|---|---|
Medicine and Dentistry | 43 | 50% |
Agricultural and Biological Sciences | 4 | 5% |
Nursing and Health Professions | 3 | 3% |
Chemistry | 2 | 2% |
Immunology and Microbiology | 1 | 1% |
Other | 6 | 7% |
Unknown | 27 | 31% |