Title |
Expression and purification of hepatitis B surface antigen S from Escherichia coli; a new simple method
|
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Published in |
BMC Research Notes, March 2012
|
DOI | 10.1186/1756-0500-5-125 |
Pubmed ID | |
Authors |
Mohamed S Elghanam, Ahmed S Attia, Hussein A Shoeb, Abd Elgawad M Hashem |
Abstract |
Hepatitis B is a liver disease primarily caused by hepatitis B virus (HBV) infection. It is distributed worldwide and associated with high mortality and morbidity rates. HBV infections can be avoided by the administration of the currently available vaccine and can be easily diagnosed through commercially available kits. Both the vaccine and the diagnostic kits depend on using the hepatitis B surface antigen (HBsAg) as an antigen. Developing countries such as, Egypt, suffer from the widespread of HBV infections and the limited resources to provide adequate supplies of either the vaccine or the diagnostic kits. Therefore the need for an easy, rapid, low cost method to produce HBsAg is urgently needed within this setting. |
X Demographics
Geographical breakdown
Country | Count | As % |
---|---|---|
Unknown | 1 | 100% |
Demographic breakdown
Type | Count | As % |
---|---|---|
Members of the public | 1 | 100% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
India | 1 | 2% |
Egypt | 1 | 2% |
Brazil | 1 | 2% |
Unknown | 57 | 95% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Researcher | 11 | 18% |
Student > Master | 9 | 15% |
Student > Bachelor | 9 | 15% |
Student > Ph. D. Student | 5 | 8% |
Student > Postgraduate | 5 | 8% |
Other | 13 | 22% |
Unknown | 8 | 13% |
Readers by discipline | Count | As % |
---|---|---|
Agricultural and Biological Sciences | 21 | 35% |
Biochemistry, Genetics and Molecular Biology | 9 | 15% |
Medicine and Dentistry | 5 | 8% |
Immunology and Microbiology | 4 | 7% |
Engineering | 3 | 5% |
Other | 8 | 13% |
Unknown | 10 | 17% |