Homocysteine and cognitive impairment; a case series in a General Practice setting

https://t.co/ej62Oow6cM "NAC also increases urinary excretion of homocysteine, leading Ventura et al to suggest that this approach may be an important associative or alternative therapy for hyperhomocysteinaemia."

https://t.co/ej62Oow6cM "Reduced glutathione is required for the conversion of cyano-B12 and hydroxo-B12 to glutathionyl-B12, prior to reduction to the enzymatically active forms of the vitamin by cobalamin reductase."

https://t.co/ej62Oow6cM "Additionally, it might facilitate intracellular vitamin B12 processing by increasing levels of reduced glutathione."

https://t.co/ej62Oow6cM "Oral NAC (600 mg daily) was added to her treatment and her family and carers noticed a significant improvement." "NAC might act as an antioxidant, reducing the effects of oxidative stress on the methionine synthase reaction."