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Triclosan promotes epicutaneous sensitization to peanut in mice

Overview of attention for article published in Clinical and Translational Allergy, April 2016
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About this Attention Score

  • In the top 25% of all research outputs scored by Altmetric
  • High Attention Score compared to outputs of the same age (90th percentile)

Mentioned by

news
1 news outlet
twitter
14 tweeters
facebook
5 Facebook pages

Citations

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10 Dimensions

Readers on

mendeley
28 Mendeley
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Title
Triclosan promotes epicutaneous sensitization to peanut in mice
Published in
Clinical and Translational Allergy, April 2016
DOI 10.1186/s13601-016-0102-2
Pubmed ID
Authors

Steven Tobar, Leticia Tordesillas, M. Cecilia Berin

Abstract

Peanut allergy is increasing in prevalence due to unknown factors. A growing body of clinical evidence suggests sensitization to peanut occurs through the skin, supported by findings in mouse models. There is a need to identify environmental factors that promote epicutaneous sensitization to peanut. Triclosan is an antimicrobial found in household products that has been associated with food sensitization in humans. We tested the impact of triclosan on epicutaneous sensitization to peanut, as well as the milk allergen α-lactalbumin (ALA). We observed that topical triclosan promoted epicutaneous sensitization to both peanut and ALA, and promoted anaphylaxis to peanut. Our results demonstrate that the mouse model of epicutaneous sensitization to foods is effective for demonstrating the clinically significant impact of environmental factors such as triclosan on food allergy.

Twitter Demographics

The data shown below were collected from the profiles of 14 tweeters who shared this research output. Click here to find out more about how the information was compiled.

Mendeley readers

The data shown below were compiled from readership statistics for 28 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 28 100%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 7 25%
Researcher 5 18%
Student > Master 4 14%
Student > Bachelor 3 11%
Unspecified 2 7%
Other 4 14%
Unknown 3 11%
Readers by discipline Count As %
Immunology and Microbiology 5 18%
Agricultural and Biological Sciences 5 18%
Medicine and Dentistry 4 14%
Chemistry 3 11%
Pharmacology, Toxicology and Pharmaceutical Science 2 7%
Other 5 18%
Unknown 4 14%

Attention Score in Context

This research output has an Altmetric Attention Score of 21. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 16 September 2016.
All research outputs
#1,433,004
of 21,735,696 outputs
Outputs from Clinical and Translational Allergy
#51
of 633 outputs
Outputs of similar age
#25,942
of 280,617 outputs
Outputs of similar age from Clinical and Translational Allergy
#1
of 1 outputs
Altmetric has tracked 21,735,696 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 93rd percentile: it's in the top 10% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 633 research outputs from this source. They typically receive more attention than average, with a mean Attention Score of 9.8. This one has done particularly well, scoring higher than 92% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 280,617 tracked outputs that were published within six weeks on either side of this one in any source. This one has done particularly well, scoring higher than 90% of its contemporaries.
We're also able to compare this research output to 1 others from the same source and published within six weeks on either side of this one. This one has scored higher than all of them