MEK inhibition remodels the active chromatin landscape and induces SOX10 genomic recruitment in BRAF(V600E) mutant melanoma cells. https://t.co/j18xflaiah
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MEK inhibition remodels the active chromatin landscape and induces SOX10 genomic recruitment in BRAF(V600E) mutant melanoma cells. https://t.co/dC4YvfgO8m https://t.co/6kNvFEd2rR
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Happy to see this work published. We described reactivation of developmental pigmentation pathway in melanoma cells in response to a MAPK pathway inhibitor & reveal MEK-SOX10 axis as a critical player. @NIH #melanoma #cancer #BRAFV600E
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RT @EpigenChromatin: A new study in "E&C" employed an integrated epigenome analysis approach to interrogate the effects of MAPK/ERK pathway…