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X Demographics
Mendeley readers
Attention Score in Context
| Title |
Molecular pathway profiling of T lymphocyte signal transduction pathways; Th1 and Th2 genomic fingerprints are defined by TCR and CD28-mediated signaling
|
|---|---|
| Published in |
BMC Immunology, March 2012
|
| DOI | 10.1186/1471-2172-13-12 |
| Pubmed ID | |
| Authors |
Ruben L Smeets, Wilco WM Fleuren, Xuehui He, Paul M Vink, Frank Wijnands, Monika Gorecka, Henri Klop, Sussane Bauerschmidt, Anja Garritsen, Hans JPM Koenen, Irma Joosten, Annemieke MH Boots, Wynand Alkema |
| Abstract |
T lymphocytes are orchestrators of adaptive immunity. Naïve T cells may differentiate into Th1, Th2, Th17 or iTreg phenotypes, depending on environmental co-stimulatory signals. To identify genes and pathways involved in differentiation of Jurkat T cells towards Th1 and Th2 subtypes we performed comprehensive transcriptome analyses of Jurkat T cells stimulated with various stimuli and pathway inhibitors. Results from these experiments were validated in a human experimental setting using whole blood and purified CD4+ Tcells. |
X Demographics
The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 1 | 100% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 1 | 100% |
Mendeley readers
The data shown below were compiled from readership statistics for 187 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 2 | 1% |
| Cyprus | 1 | <1% |
| Germany | 1 | <1% |
| Taiwan | 1 | <1% |
| Unknown | 182 | 97% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Researcher | 53 | 28% |
| Student > Ph. D. Student | 32 | 17% |
| Student > Bachelor | 30 | 16% |
| Student > Master | 21 | 11% |
| Student > Postgraduate | 9 | 5% |
| Other | 20 | 11% |
| Unknown | 22 | 12% |
| Readers by discipline | Count | As % |
|---|---|---|
| Agricultural and Biological Sciences | 64 | 34% |
| Biochemistry, Genetics and Molecular Biology | 35 | 19% |
| Immunology and Microbiology | 30 | 16% |
| Medicine and Dentistry | 17 | 9% |
| Pharmacology, Toxicology and Pharmaceutical Science | 3 | 2% |
| Other | 11 | 6% |
| Unknown | 27 | 14% |
Attention Score in Context
This research output has an Altmetric Attention Score of 4. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 05 June 2023.
All research outputs
#6,911,735
of 22,663,969 outputs
Outputs from BMC Immunology
#116
of 588 outputs
Outputs of similar age
#46,449
of 156,709 outputs
Outputs of similar age from BMC Immunology
#3
of 12 outputs
Altmetric has tracked 22,663,969 research outputs across all sources so far. This one has received more attention than most of these and is in the 68th percentile.
So far Altmetric has tracked 588 research outputs from this source. They receive a mean Attention Score of 3.7. This one has done well, scoring higher than 78% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 156,709 tracked outputs that were published within six weeks on either side of this one in any source. This one has gotten more attention than average, scoring higher than 68% of its contemporaries.
We're also able to compare this research output to 12 others from the same source and published within six weeks on either side of this one. This one has done well, scoring higher than 75% of its contemporaries.