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Increased levels of prolactin receptor expression correlate with the early onset of lupus symptoms and increased numbers of transitional-1 B cells after prolactin treatment

Overview of attention for article published in BMC Immunology, March 2012
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Title
Increased levels of prolactin receptor expression correlate with the early onset of lupus symptoms and increased numbers of transitional-1 B cells after prolactin treatment
Published in
BMC Immunology, March 2012
DOI 10.1186/1471-2172-13-11
Pubmed ID
Authors

Yadira Ledesma-Soto, Francisco Blanco-Favela, Ezequiel M Fuentes-Pananá, Emiliano Tesoro-Cruz, Rafael Hernández-González, Lourdes Arriaga-Pizano, María V Legorreta-Haquet, Eduardo Montoya-Diaz, Luis Chávez-Sánchez, María E Castro-Mussot, Adriana K Chávez-Rueda

Abstract

Prolactin is secreted from the pituitary gland and other organs, as well as by cells such as lymphocytes. Prolactin has an immunostimulatory effect and is associated with autoimmune diseases that are characterised by abnormal B cell activation, such as systemic lupus erythematosus (SLE). Our aim was to determine if different splenic B cell subsets express the prolactin receptor and if the presence of prolactin influences these B cell subsets and correlates with development of lupus.

X Demographics

X Demographics

The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 26 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 26 100%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 5 19%
Researcher 3 12%
Student > Bachelor 2 8%
Student > Postgraduate 2 8%
Professor > Associate Professor 2 8%
Other 5 19%
Unknown 7 27%
Readers by discipline Count As %
Agricultural and Biological Sciences 6 23%
Medicine and Dentistry 6 23%
Biochemistry, Genetics and Molecular Biology 2 8%
Nursing and Health Professions 2 8%
Immunology and Microbiology 1 4%
Other 2 8%
Unknown 7 27%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 17 March 2012.
All research outputs
#15,242,707
of 22,663,969 outputs
Outputs from BMC Immunology
#319
of 588 outputs
Outputs of similar age
#100,042
of 156,320 outputs
Outputs of similar age from BMC Immunology
#9
of 12 outputs
Altmetric has tracked 22,663,969 research outputs across all sources so far. This one is in the 22nd percentile – i.e., 22% of other outputs scored the same or lower than it.
So far Altmetric has tracked 588 research outputs from this source. They receive a mean Attention Score of 3.7. This one is in the 36th percentile – i.e., 36% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 156,320 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 25th percentile – i.e., 25% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 12 others from the same source and published within six weeks on either side of this one. This one is in the 25th percentile – i.e., 25% of its contemporaries scored the same or lower than it.