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Oil from pumpkin (Cucurbita pepo L.) seeds: evaluation of its functional properties on wound healing in rats

Overview of attention for article published in Lipids in Health and Disease, April 2016
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About this Attention Score

  • In the top 5% of all research outputs scored by Altmetric
  • High Attention Score compared to outputs of the same age (95th percentile)
  • High Attention Score compared to outputs of the same age and source (97th percentile)

Mentioned by

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5 news outlets
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17 X users
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3 YouTube creators

Citations

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132 Dimensions

Readers on

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273 Mendeley
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Title
Oil from pumpkin (Cucurbita pepo L.) seeds: evaluation of its functional properties on wound healing in rats
Published in
Lipids in Health and Disease, April 2016
DOI 10.1186/s12944-016-0237-0
Pubmed ID
Authors

Sana Bardaa, Nihed Ben Halima, Fatma Aloui, Riadh Ben Mansour, Hazem Jabeur, Mohamed Bouaziz, Zouheir Sahnoun

Abstract

Increasing natural drug demand for pharmaceutical uses has encouraged scientifics all over the world to explore medicinal plants recognized as efficient remedies. In this context, extracted oil from pumpkin seeds (Cucurbita pepo L.) is an interesting target, as it is composed with prominent pharmacological properties to possible wound healing treatments. The composition and content of certain bioactive constituents of the cold pressed oil obtained from pumpkin seeds (Cucurbita pepo L.) were analyzed and studied for their wound healing properties. Uniform wounds were induced on the dorsum of 18 rats, randomly divided into three groups. The wounds were photographed, and topically treated with saline solution (control group), 0.13 mg/mm(2) of a reference drug ("Cicaflora cream®"), and 0.52 μl/mm(2) of pumpkin's oil each 2 days until the first group is completely healing and so far biopsies were histologically assessed. The composition and content of tocopherols, fatty acids, and phytosterols were determined. The results showed an excellent quality of pumpkin oil with high content of polyunsaturated fatty acids (Linoleic acid: 50.88 ± 0.106 g/100 g of total fatty acids), tocopherols (280 ppm) and sterols (2086.5 ± 19.092 ppm). High content of these bioactive components were in agreement with an efficient wound healing by the mean of an in vivo study. In fact, morphometric assessment and histological findings revealed healed biopsies from pumpkin oil treated group of rats, unlike untreated group, and a full re-epithelialization with reappearance of skin appendages and well organized collagen fibers without inflammatory cells. This study showed the significance of oil from pumpkin seeds (Cucurbita pepo L.) as a promising drug to healing wounds in animal assays. As a whole, pumpkin's oil would be recommended in the nutritional and medicinal purposes.

X Demographics

X Demographics

The data shown below were collected from the profiles of 17 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 273 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 273 100%

Demographic breakdown

Readers by professional status Count As %
Student > Master 33 12%
Student > Bachelor 33 12%
Student > Ph. D. Student 25 9%
Researcher 21 8%
Other 14 5%
Other 40 15%
Unknown 107 39%
Readers by discipline Count As %
Agricultural and Biological Sciences 41 15%
Chemistry 23 8%
Pharmacology, Toxicology and Pharmaceutical Science 20 7%
Biochemistry, Genetics and Molecular Biology 18 7%
Medicine and Dentistry 17 6%
Other 37 14%
Unknown 117 43%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 53. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 14 January 2023.
All research outputs
#748,057
of 24,313,168 outputs
Outputs from Lipids in Health and Disease
#54
of 1,542 outputs
Outputs of similar age
#13,817
of 305,533 outputs
Outputs of similar age from Lipids in Health and Disease
#2
of 34 outputs
Altmetric has tracked 24,313,168 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 96th percentile: it's in the top 5% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 1,542 research outputs from this source. They typically receive more attention than average, with a mean Attention Score of 8.6. This one has done particularly well, scoring higher than 96% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 305,533 tracked outputs that were published within six weeks on either side of this one in any source. This one has done particularly well, scoring higher than 95% of its contemporaries.
We're also able to compare this research output to 34 others from the same source and published within six weeks on either side of this one. This one has done particularly well, scoring higher than 97% of its contemporaries.