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Annexins family: insights into their functions and potential role in pathogenesis of sarcoidosis

Overview of attention for article published in Journal of Translational Medicine, April 2016
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About this Attention Score

  • Good Attention Score compared to outputs of the same age (69th percentile)
  • Good Attention Score compared to outputs of the same age and source (78th percentile)

Mentioned by

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3 X users
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1 patent

Citations

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81 Dimensions

Readers on

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145 Mendeley
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Title
Annexins family: insights into their functions and potential role in pathogenesis of sarcoidosis
Published in
Journal of Translational Medicine, April 2016
DOI 10.1186/s12967-016-0843-7
Pubmed ID
Authors

Mehdi Mirsaeidi, Sanaz Gidfar, Ann Vu, Dean Schraufnagel

Abstract

Annexins are Ca(2+)-regulated phospholipid-binding proteins that play an important role in the cell life cycle, exocytosis, and apoptosis. Annexin A11 is one of the oldest vertebrate annexins that has a crucial role in sarcoidosis pathogenesis. The mechanism of effect in sarcoidosis granuloma cells may be due to alterations in apoptosis. Immune cells with a specific mutation at protein location 230 are resistant to apoptosis and consequently have continued effects on inflammation and progression of sarcoidosis. The mechanism of action of annexin A11 may be based upon alterations in delivering calcium to two different apoptosis pathways (caspase and P53).

X Demographics

X Demographics

The data shown below were collected from the profiles of 3 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 145 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 145 100%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 32 22%
Student > Master 18 12%
Researcher 17 12%
Student > Bachelor 14 10%
Student > Doctoral Student 11 8%
Other 17 12%
Unknown 36 25%
Readers by discipline Count As %
Biochemistry, Genetics and Molecular Biology 37 26%
Medicine and Dentistry 18 12%
Agricultural and Biological Sciences 16 11%
Chemistry 5 3%
Immunology and Microbiology 4 3%
Other 20 14%
Unknown 45 31%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 5. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 16 August 2018.
All research outputs
#6,300,477
of 22,862,742 outputs
Outputs from Journal of Translational Medicine
#952
of 4,001 outputs
Outputs of similar age
#89,739
of 300,876 outputs
Outputs of similar age from Journal of Translational Medicine
#18
of 84 outputs
Altmetric has tracked 22,862,742 research outputs across all sources so far. This one has received more attention than most of these and is in the 72nd percentile.
So far Altmetric has tracked 4,001 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 10.5. This one has done well, scoring higher than 75% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 300,876 tracked outputs that were published within six weeks on either side of this one in any source. This one has gotten more attention than average, scoring higher than 69% of its contemporaries.
We're also able to compare this research output to 84 others from the same source and published within six weeks on either side of this one. This one has done well, scoring higher than 78% of its contemporaries.