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Inhibition of nuclear factor kappa-B signaling reduces growth in medulloblastoma in vivo

Overview of attention for article published in BMC Cancer, April 2011
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Title
Inhibition of nuclear factor kappa-B signaling reduces growth in medulloblastoma in vivo
Published in
BMC Cancer, April 2011
DOI 10.1186/1471-2407-11-136
Pubmed ID
Authors

Susan E Spiller, Naomi J Logsdon, Lindsey A Deckard, Harald Sontheimer

Abstract

Medulloblastoma is a highly malignant pediatric brain tumor that requires surgery, whole brain and spine irradiation, and intense chemotherapy for treatment. A more sophisticated understanding of the pathophysiology of medulloblastoma is needed to successfully reduce the intensity of treatment and improve outcomes. Nuclear factor kappa-B (NFκB) is a signaling pathway that controls transcriptional activation of genes important for tight regulation of many cellular processes and is aberrantly expressed in many types of cancer.

X Demographics

X Demographics

The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 61 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United States 2 3%
Spain 1 2%
Germany 1 2%
Austria 1 2%
Unknown 56 92%

Demographic breakdown

Readers by professional status Count As %
Researcher 16 26%
Student > Ph. D. Student 11 18%
Other 8 13%
Student > Bachelor 6 10%
Student > Master 5 8%
Other 12 20%
Unknown 3 5%
Readers by discipline Count As %
Agricultural and Biological Sciences 22 36%
Medicine and Dentistry 16 26%
Biochemistry, Genetics and Molecular Biology 5 8%
Neuroscience 5 8%
Immunology and Microbiology 3 5%
Other 5 8%
Unknown 5 8%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 26 March 2012.
All research outputs
#19,528,590
of 24,022,746 outputs
Outputs from BMC Cancer
#5,646
of 8,536 outputs
Outputs of similar age
#98,242
of 111,882 outputs
Outputs of similar age from BMC Cancer
#31
of 35 outputs
Altmetric has tracked 24,022,746 research outputs across all sources so far. This one is in the 10th percentile – i.e., 10% of other outputs scored the same or lower than it.
So far Altmetric has tracked 8,536 research outputs from this source. They receive a mean Attention Score of 4.5. This one is in the 21st percentile – i.e., 21% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 111,882 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 6th percentile – i.e., 6% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 35 others from the same source and published within six weeks on either side of this one. This one is in the 1st percentile – i.e., 1% of its contemporaries scored the same or lower than it.