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Early warning score: a dynamic marker of severity and prognosis in patients with Gram-negative bacteraemia and sepsis

Overview of attention for article published in Annals of Clinical Microbiology and Antimicrobials, April 2016
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  • Good Attention Score compared to outputs of the same age (69th percentile)
  • Above-average Attention Score compared to outputs of the same age and source (52nd percentile)

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Title
Early warning score: a dynamic marker of severity and prognosis in patients with Gram-negative bacteraemia and sepsis
Published in
Annals of Clinical Microbiology and Antimicrobials, April 2016
DOI 10.1186/s12941-016-0139-z
Pubmed ID
Authors

Mahableshwar Albur, Fergus Hamilton, Alasdair P. MacGowan

Abstract

Early Warning Score (EWS) is a physiological composite score of six bedside vital parameters, routinely used in UK hospitals. We evaluated the prognostic ability of EWS in Gram-negative bacteraemia causing sepsis. We prospectively evaluated EWS as a marker of severity and prognosis in adult patients with Gram-negative bacteraemia. All adult patients with Gram-negative bacteraemia admitted to our tertiary Teaching hospital of the National Health Service in England were enrolled over 1 year period. The highest daily EWS score was recorded from 7 days before to 14 days after the date of onset of bacteraemia. The primary outcome was 28-day mortality. A total of 245 consecutive adult patients with Gram-negative bacteraemia with sepsis were enrolled. On multivariate analysis, following variables were associated with death for every single unit change (odds ratio in the brackets): higher age (1.05), lower mean arterial pressure (1.03), lower serum bicarbonate (1.08), higher EWS (1.27), higher SOFA score (1.36), hospital-onset of infection (5.43) and need for vasopressor agents (16.4). EWS on day 0, 1, 2, and average 14-day score were significantly higher in patients who died by 28 days from the onset of bacteraemia [95 % CI 0.4-0.6] p < 0.001. A stepwise rise in EWS and failure of improvement in EWS by 2 points 48 h after the onset of bacteraemia were associated with poor outcome. EWS is a simple and cost-effective bedside tool for the assessment of severity and prognosis of sepsis caused by Gram-negative bacteraemia.

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X Demographics

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Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 99 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United Kingdom 1 1%
Unknown 98 99%

Demographic breakdown

Readers by professional status Count As %
Student > Bachelor 20 20%
Other 11 11%
Researcher 10 10%
Student > Master 9 9%
Student > Ph. D. Student 7 7%
Other 20 20%
Unknown 22 22%
Readers by discipline Count As %
Medicine and Dentistry 39 39%
Nursing and Health Professions 10 10%
Biochemistry, Genetics and Molecular Biology 5 5%
Immunology and Microbiology 3 3%
Agricultural and Biological Sciences 2 2%
Other 14 14%
Unknown 26 26%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 5. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 13 September 2017.
All research outputs
#6,996,305
of 25,284,710 outputs
Outputs from Annals of Clinical Microbiology and Antimicrobials
#140
of 673 outputs
Outputs of similar age
#91,212
of 307,872 outputs
Outputs of similar age from Annals of Clinical Microbiology and Antimicrobials
#10
of 19 outputs
Altmetric has tracked 25,284,710 research outputs across all sources so far. This one has received more attention than most of these and is in the 72nd percentile.
So far Altmetric has tracked 673 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 6.4. This one has done well, scoring higher than 78% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 307,872 tracked outputs that were published within six weeks on either side of this one in any source. This one has gotten more attention than average, scoring higher than 69% of its contemporaries.
We're also able to compare this research output to 19 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 52% of its contemporaries.