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Regulation of mitochondrial functions by protein phosphorylation and dephosphorylation

Overview of attention for article published in Cell & Bioscience, April 2016
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About this Attention Score

  • In the top 25% of all research outputs scored by Altmetric
  • Among the highest-scoring outputs from this source (#33 of 372)
  • Good Attention Score compared to outputs of the same age (75th percentile)
  • High Attention Score compared to outputs of the same age and source (88th percentile)

Mentioned by

3 tweeters
1 Facebook page
1 Wikipedia page


61 Dimensions

Readers on

136 Mendeley
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Regulation of mitochondrial functions by protein phosphorylation and dephosphorylation
Published in
Cell & Bioscience, April 2016
DOI 10.1186/s13578-016-0089-3
Pubmed ID

Sangbin Lim, Kelly R. Smith, Ssang-Taek Steve Lim, Rong Tian, Jianrong Lu, Ming Tan


The mitochondria are double membrane-bound organelles found in most eukaryotic cells. They generate most of the cell's energy supply of adenosine triphosphate (ATP). Protein phosphorylation and dephosphorylation are critical mechanisms in the regulation of cell signaling networks and are essential for almost all the cellular functions. For many decades, mitochondria were considered autonomous organelles merely functioning to generate energy for cells to survive and proliferate, and were thought to be independent of the cellular signaling networks. Consequently, phosphorylation and dephosphorylation processes of mitochondrial kinases and phosphatases were largely neglected. However, evidence accumulated in recent years on mitochondria-localized kinases/phosphatases has changed this longstanding view. Mitochondria are increasingly recognized as a hub for cell signaling, and many kinases and phosphatases have been reported to localize in mitochondria and play important functions. However, the strength of the evidence on mitochondrial localization and the activities of the reported kinases and phosphatases vary greatly, and the detailed mechanisms on how these kinases/phosphatases translocate to mitochondria, their subsequent function, and the physiological and pathological implications of their localization are still poorly understood. Here, we provide an updated perspective on the recent advancement in this area, with an emphasis on the implications of mitochondrial kinases/phosphatases in cancer and several other diseases.

Twitter Demographics

The data shown below were collected from the profiles of 3 tweeters who shared this research output. Click here to find out more about how the information was compiled.

Mendeley readers

The data shown below were compiled from readership statistics for 136 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United Kingdom 1 <1%
Chile 1 <1%
United States 1 <1%
Brazil 1 <1%
Unknown 132 97%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 35 26%
Researcher 24 18%
Student > Bachelor 19 14%
Student > Master 18 13%
Student > Doctoral Student 7 5%
Other 21 15%
Unknown 12 9%
Readers by discipline Count As %
Biochemistry, Genetics and Molecular Biology 54 40%
Agricultural and Biological Sciences 27 20%
Medicine and Dentistry 10 7%
Pharmacology, Toxicology and Pharmaceutical Science 9 7%
Chemistry 7 5%
Other 16 12%
Unknown 13 10%

Attention Score in Context

This research output has an Altmetric Attention Score of 6. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 15 March 2019.
All research outputs
of 14,501,726 outputs
Outputs from Cell & Bioscience
of 372 outputs
Outputs of similar age
of 263,684 outputs
Outputs of similar age from Cell & Bioscience
of 9 outputs
Altmetric has tracked 14,501,726 research outputs across all sources so far. Compared to these this one has done well and is in the 77th percentile: it's in the top 25% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 372 research outputs from this source. They receive a mean Attention Score of 1.9. This one has done particularly well, scoring higher than 91% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 263,684 tracked outputs that were published within six weeks on either side of this one in any source. This one has done well, scoring higher than 75% of its contemporaries.
We're also able to compare this research output to 9 others from the same source and published within six weeks on either side of this one. This one has scored higher than all of them