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X Demographics
Mendeley readers
| Title |
Validated spectrophotometric methods for determination of Alendronate sodium in tablets through nucleophilic aromatic substitution reactions
|
|---|---|
| Published in |
BMC Chemistry, April 2012
|
| DOI | 10.1186/1752-153x-6-25 |
| Pubmed ID | |
| Authors |
Mohamed I Walash, Mohamed E-S Metwally, Manal Eid, Rania N El-Shaheny |
| Abstract |
Alendronate (ALD) is a member of the bisphosphonate family which is used for the treatment of osteoporosis, bone metastasis, Paget's disease, hypocalcaemia associated with malignancy and other conditions that feature bone fragility. ALD is a non-chromophoric compound so its determination by conventional spectrophotometric methods is not possible. So two derivatization reactions were proposed for determination of ALD through the reaction with 4-chloro-7-nitrobenzo-2-oxa-1,3-diazole (NBD-Cl) and 2,4-dinitrofluorobenzene (DNFB) as chromogenic derivatizing reagents. |
X Demographics
The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Germany | 1 | 100% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Scientists | 1 | 100% |
Mendeley readers
The data shown below were compiled from readership statistics for 50 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 1 | 2% |
| Unknown | 49 | 98% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Master | 9 | 18% |
| Researcher | 8 | 16% |
| Student > Bachelor | 7 | 14% |
| Student > Ph. D. Student | 4 | 8% |
| Student > Doctoral Student | 3 | 6% |
| Other | 8 | 16% |
| Unknown | 11 | 22% |
| Readers by discipline | Count | As % |
|---|---|---|
| Chemistry | 11 | 22% |
| Pharmacology, Toxicology and Pharmaceutical Science | 9 | 18% |
| Agricultural and Biological Sciences | 3 | 6% |
| Engineering | 3 | 6% |
| Biochemistry, Genetics and Molecular Biology | 2 | 4% |
| Other | 5 | 10% |
| Unknown | 17 | 34% |