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Crosstalk between HIV and hepatitis C virus during co-infection

Overview of attention for article published in BMC Medicine, April 2012
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About this Attention Score

  • In the top 25% of all research outputs scored by Altmetric
  • High Attention Score compared to outputs of the same age (80th percentile)

Mentioned by

twitter
7 tweeters
facebook
3 Facebook pages

Citations

dimensions_citation
8 Dimensions

Readers on

mendeley
21 Mendeley
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Title
Crosstalk between HIV and hepatitis C virus during co-infection
Published in
BMC Medicine, April 2012
DOI 10.1186/1741-7015-10-32
Pubmed ID
Authors

Paul J Rider, Fenyong Liu

Abstract

An estimated one-third of individuals positive for HIV are also infected with hepatitis C virus (HCV). Chronic infection with HCV can lead to serious liver disease including cirrhosis and hepatocellular carcinoma. Liver-related disease is among the leading causes of death in patients with HIV, and individuals with HIV and HCV co-infection are found to progress more rapidly to serious liver disease than mono-infected individuals. The mechanism by which HIV affects HCV infection in the absence of immunosuppression by HIV is currently unknown. In a recent article published in BMC Immunology, Qu et al. demonstrated that HIV tat is capable of inducing IP-10 expression. Further, they were able to show that HIV tat, when added to cells, was able to enhance the replication of HCV. Importantly, the increase in HCV replication by tat was found to be dependent on IP-10. This work has important implications for understanding the effect HIV has on the outcome of HCV infection in co-infected individuals. The findings of Qu et al. may inform the design of intervention and treatment strategies for co-infected individuals.Please see related article: http://www.biomedcentral.com/1471-2172/13/15.

Twitter Demographics

The data shown below were collected from the profiles of 7 tweeters who shared this research output. Click here to find out more about how the information was compiled.

Mendeley readers

The data shown below were compiled from readership statistics for 21 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United Kingdom 2 10%
Portugal 1 5%
Netherlands 1 5%
China 1 5%
Spain 1 5%
Unknown 15 71%

Demographic breakdown

Readers by professional status Count As %
Researcher 9 43%
Student > Ph. D. Student 4 19%
Student > Master 4 19%
Other 2 10%
Lecturer 1 5%
Other 1 5%
Readers by discipline Count As %
Medicine and Dentistry 6 29%
Agricultural and Biological Sciences 4 19%
Immunology and Microbiology 4 19%
Biochemistry, Genetics and Molecular Biology 1 5%
Business, Management and Accounting 1 5%
Other 3 14%
Unknown 2 10%

Attention Score in Context

This research output has an Altmetric Attention Score of 7. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 10 November 2012.
All research outputs
#3,436,841
of 17,351,915 outputs
Outputs from BMC Medicine
#1,730
of 2,703 outputs
Outputs of similar age
#25,098
of 131,791 outputs
Outputs of similar age from BMC Medicine
#2
of 3 outputs
Altmetric has tracked 17,351,915 research outputs across all sources so far. Compared to these this one has done well and is in the 80th percentile: it's in the top 25% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 2,703 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 38.9. This one is in the 35th percentile – i.e., 35% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 131,791 tracked outputs that were published within six weeks on either side of this one in any source. This one has done well, scoring higher than 80% of its contemporaries.
We're also able to compare this research output to 3 others from the same source and published within six weeks on either side of this one.