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BRCA1 as tumor suppressor: lord without its RING?

Overview of attention for article published in Breast Cancer Research, April 2012
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Title
BRCA1 as tumor suppressor: lord without its RING?
Published in
Breast Cancer Research, April 2012
DOI 10.1186/bcr3118
Pubmed ID
Authors

Andrew EH Elia, Stephen J Elledge

Abstract

BRCA1 is a tumor suppressor with critical roles in the maintenance of genomic stability. It encodes a large protein with an amino-terminal RING domain that possesses ubiquitin-ligase activity. Given the occurrence of numerous cancer-causing mutations within its RING domain, investigators have long suspected that BRCA1's ubiquitin ligase is important for its tumor suppression and DNA repair activities. Using genetically engineered mouse models, two recent studies shed light on this age-old hypothesis.

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X Demographics

The data shown below were collected from the profiles of 3 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 41 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 41 100%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 11 27%
Researcher 10 24%
Student > Doctoral Student 4 10%
Student > Master 4 10%
Student > Bachelor 2 5%
Other 4 10%
Unknown 6 15%
Readers by discipline Count As %
Agricultural and Biological Sciences 15 37%
Biochemistry, Genetics and Molecular Biology 13 32%
Medicine and Dentistry 4 10%
Chemistry 2 5%
Pharmacology, Toxicology and Pharmaceutical Science 1 2%
Other 0 0%
Unknown 6 15%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 2. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 10 April 2012.
All research outputs
#16,048,318
of 25,374,917 outputs
Outputs from Breast Cancer Research
#1,430
of 2,053 outputs
Outputs of similar age
#105,179
of 174,010 outputs
Outputs of similar age from Breast Cancer Research
#30
of 40 outputs
Altmetric has tracked 25,374,917 research outputs across all sources so far. This one is in the 34th percentile – i.e., 34% of other outputs scored the same or lower than it.
So far Altmetric has tracked 2,053 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 12.2. This one is in the 28th percentile – i.e., 28% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 174,010 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 37th percentile – i.e., 37% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 40 others from the same source and published within six weeks on either side of this one. This one is in the 17th percentile – i.e., 17% of its contemporaries scored the same or lower than it.