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X Demographics
Mendeley readers
Attention Score in Context
| Title |
Zinc Finger Nucleases as tools to understand and treat human diseases
|
|---|---|
| Published in |
BMC Medicine, July 2010
|
| DOI | 10.1186/1741-7015-8-42 |
| Pubmed ID | |
| Authors |
David Davis, David Stokoe |
| Abstract |
Recent work has shown that it is possible to target regulatory elements to DNA sequences of an investigator's choosing, increasing the armamentarium for probing gene function. In this review, we discuss the development and use of designer zinc finger proteins (ZFPs) as sequence specific tools. While the main focus of this review is to discuss the attachment of the FokI nuclease to ZFPs and the ability of the resulting fusion protein (termed zinc finger nucleases (ZFNs)) to genomically manipulate a gene of interest, we will also cover the utility of other functional domains, such as transcriptional activators and repressors, and highlight how these are being used as discovery and therapeutic tools. |
X Demographics
The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 1 | 100% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 1 | 100% |
Mendeley readers
The data shown below were compiled from readership statistics for 145 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 5 | 3% |
| Spain | 2 | 1% |
| France | 1 | <1% |
| South Africa | 1 | <1% |
| Belarus | 1 | <1% |
| Germany | 1 | <1% |
| India | 1 | <1% |
| Mexico | 1 | <1% |
| Unknown | 132 | 91% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Researcher | 38 | 26% |
| Student > Ph. D. Student | 35 | 24% |
| Student > Master | 17 | 12% |
| Student > Bachelor | 12 | 8% |
| Student > Doctoral Student | 6 | 4% |
| Other | 17 | 12% |
| Unknown | 20 | 14% |
| Readers by discipline | Count | As % |
|---|---|---|
| Agricultural and Biological Sciences | 74 | 51% |
| Biochemistry, Genetics and Molecular Biology | 24 | 17% |
| Medicine and Dentistry | 16 | 11% |
| Chemistry | 6 | 4% |
| Pharmacology, Toxicology and Pharmaceutical Science | 1 | <1% |
| Other | 4 | 3% |
| Unknown | 20 | 14% |
Attention Score in Context
This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 28 October 2012.
All research outputs
#15,242,847
of 22,664,267 outputs
Outputs from BMC Medicine
#3,023
of 3,397 outputs
Outputs of similar age
#75,552
of 93,452 outputs
Outputs of similar age from BMC Medicine
#14
of 15 outputs
Altmetric has tracked 22,664,267 research outputs across all sources so far. This one is in the 22nd percentile – i.e., 22% of other outputs scored the same or lower than it.
So far Altmetric has tracked 3,397 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 43.6. This one is in the 8th percentile – i.e., 8% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 93,452 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 11th percentile – i.e., 11% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 15 others from the same source and published within six weeks on either side of this one. This one is in the 6th percentile – i.e., 6% of its contemporaries scored the same or lower than it.