Title |
Aestivation and hypoxia-related events share common silent neuron trafficking processes
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Published in |
BMC Neuroscience, April 2012
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DOI | 10.1186/1471-2202-13-39 |
Pubmed ID | |
Authors |
Giuseppina Giusi, Merylin Zizza, Rosa Maria Facciolo, Shit Fun Chew, Yuen Kwong Ip, Marcello Canonaco |
Abstract |
The availability of oxygen is a limiting factor for neuronal survival since low levels account not only for the impairment of physiological activities such as sleep-wake cycle, but above all for ischemic-like neurodegenerative disorders. In an attempt to improve our knowledge concerning the type of molecular mechanisms operating during stressful states like those of hypoxic conditions, attention was focused on eventual transcriptional alterations of some key AMPAergic silent neuronal receptor subtypes (GluR1 and GluR2) along with HSPs and HIF-1α during either a normoxic or a hypoxic aestivation of a typical aquatic aestivator, i.e. the lungfish (Protopterus annectens). |
X Demographics
Geographical breakdown
Country | Count | As % |
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United States | 1 | 100% |
Demographic breakdown
Type | Count | As % |
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Members of the public | 1 | 100% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
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Unknown | 16 | 100% |
Demographic breakdown
Readers by professional status | Count | As % |
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Other | 2 | 13% |
Student > Bachelor | 2 | 13% |
Researcher | 2 | 13% |
Student > Doctoral Student | 1 | 6% |
Professor | 1 | 6% |
Other | 4 | 25% |
Unknown | 4 | 25% |
Readers by discipline | Count | As % |
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Biochemistry, Genetics and Molecular Biology | 2 | 13% |
Agricultural and Biological Sciences | 2 | 13% |
Neuroscience | 2 | 13% |
Unspecified | 1 | 6% |
Nursing and Health Professions | 1 | 6% |
Other | 3 | 19% |
Unknown | 5 | 31% |