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Antifibrotic effects of curcumin are associated with overexpression of cathepsins K and L in bleomycin treated mice and human fibroblasts

Overview of attention for article published in Respiratory Research, December 2011
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About this Attention Score

  • In the top 25% of all research outputs scored by Altmetric
  • High Attention Score compared to outputs of the same age (85th percentile)
  • High Attention Score compared to outputs of the same age and source (84th percentile)

Mentioned by

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11 X users

Citations

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41 Mendeley
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Title
Antifibrotic effects of curcumin are associated with overexpression of cathepsins K and L in bleomycin treated mice and human fibroblasts
Published in
Respiratory Research, December 2011
DOI 10.1186/1465-9921-12-154
Pubmed ID
Authors

Dongwei Zhang, Chuangfang Huang, Changfu Yang, Renzuo J Liu, Jifeng Wang, Jianzhao Niu, Dieter Brömme

Abstract

Lung fibrosis is characterized by fibroblast proliferation and the deposition of collagens. Curcumin, a polyphenol antioxidant from the spice tumeric, has been shown to effectively counteract fibroblast proliferation and reducing inflammation and fibrotic progression in animal models of bleomycin-induced lung injury. However, there is little mechanistic insight in the biological activity of curcumin. Here, we study the effects of curcumin on the expression and activity of cathepsins which have been implicated in the development of fibrotic lung diseases.

X Demographics

X Demographics

The data shown below were collected from the profiles of 11 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 41 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 41 100%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 9 22%
Student > Master 6 15%
Researcher 5 12%
Student > Postgraduate 3 7%
Student > Bachelor 2 5%
Other 3 7%
Unknown 13 32%
Readers by discipline Count As %
Biochemistry, Genetics and Molecular Biology 7 17%
Agricultural and Biological Sciences 7 17%
Pharmacology, Toxicology and Pharmaceutical Science 3 7%
Immunology and Microbiology 2 5%
Sports and Recreations 2 5%
Other 6 15%
Unknown 14 34%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 8. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 03 February 2024.
All research outputs
#4,535,152
of 25,374,647 outputs
Outputs from Respiratory Research
#563
of 3,062 outputs
Outputs of similar age
#35,033
of 246,216 outputs
Outputs of similar age from Respiratory Research
#11
of 69 outputs
Altmetric has tracked 25,374,647 research outputs across all sources so far. Compared to these this one has done well and is in the 82nd percentile: it's in the top 25% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 3,062 research outputs from this source. They typically receive more attention than average, with a mean Attention Score of 7.9. This one has done well, scoring higher than 81% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 246,216 tracked outputs that were published within six weeks on either side of this one in any source. This one has done well, scoring higher than 85% of its contemporaries.
We're also able to compare this research output to 69 others from the same source and published within six weeks on either side of this one. This one has done well, scoring higher than 84% of its contemporaries.