Title |
Oral HPV infection and MHC class II deficiency (A study of two cases with atypical outcome)
|
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Published in |
Clinical and Molecular Allergy, April 2012
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DOI | 10.1186/1476-7961-10-6 |
Pubmed ID | |
Authors |
Naouel Guirat-Dhouib, Yemen Baccar, Imène Ben Mustapha, Monia Ouederni, Sameh Chouaibi, Nadia El Fekih, Mohamed Ridha Barbouche, Bassima Fezaa, Ridha Kouki, Slama Hmida, Fethi Mellouli, Mohamed Bejaoui |
Abstract |
Major histocompatibility complex class II deficiency, also referred to as bare lymphocyte syndrome is a rare primary Immunodeficiency disorder characterized by a profondly deficient human leukocyte antigen class II expression and a lack of cellular and humoral immune responses to foreign antigens. Clinical manifestations include extreme susceptibility to viral, bacterial, and fungal infections. The infections begin in the first year of life and involve usually the respiratory system and the gastrointestinal tract. Severe malabsorption with failure to thrive ensues, often leading to death in early childhood. Bone marrow transplantation is the curative treatment. |
X Demographics
Geographical breakdown
Country | Count | As % |
---|---|---|
United States | 1 | 50% |
Unknown | 1 | 50% |
Demographic breakdown
Type | Count | As % |
---|---|---|
Members of the public | 2 | 100% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
Unknown | 21 | 100% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Master | 4 | 19% |
Student > Doctoral Student | 3 | 14% |
Other | 2 | 10% |
Professor | 2 | 10% |
Student > Ph. D. Student | 2 | 10% |
Other | 4 | 19% |
Unknown | 4 | 19% |
Readers by discipline | Count | As % |
---|---|---|
Medicine and Dentistry | 7 | 33% |
Biochemistry, Genetics and Molecular Biology | 4 | 19% |
Social Sciences | 2 | 10% |
Psychology | 1 | 5% |
Unspecified | 1 | 5% |
Other | 2 | 10% |
Unknown | 4 | 19% |