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Genome-wide analysis of Pax8 binding provides new insights into thyroid functions

Overview of attention for article published in BMC Genomics, April 2012
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Title
Genome-wide analysis of Pax8 binding provides new insights into thyroid functions
Published in
BMC Genomics, April 2012
DOI 10.1186/1471-2164-13-147
Pubmed ID
Authors

Sergio Ruiz-Llorente, Enrique Carrillo Santa de Pau, Ana Sastre-Perona, Cristina Montero-Conde, Gonzalo Gómez-López, James A Fagin, Alfonso Valencia, David G Pisano, Pilar Santisteban

Abstract

The transcription factor Pax8 is essential for the differentiation of thyroid cells. However, there are few data on genes transcriptionally regulated by Pax8 other than thyroid-related genes. To better understand the role of Pax8 in the biology of thyroid cells, we obtained transcriptional profiles of Pax8-silenced PCCl3 thyroid cells using whole genome expression arrays and integrated these signals with global cis-regulatory sequencing studies performed by ChIP-Seq analysis

X Demographics

X Demographics

The data shown below were collected from the profiles of 2 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 45 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United Kingdom 1 2%
Spain 1 2%
Unknown 43 96%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 13 29%
Researcher 13 29%
Student > Master 3 7%
Student > Doctoral Student 2 4%
Professor 2 4%
Other 8 18%
Unknown 4 9%
Readers by discipline Count As %
Agricultural and Biological Sciences 19 42%
Biochemistry, Genetics and Molecular Biology 12 27%
Medicine and Dentistry 5 11%
Environmental Science 1 2%
Social Sciences 1 2%
Other 1 2%
Unknown 6 13%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 2. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 25 April 2012.
All research outputs
#14,143,926
of 22,664,644 outputs
Outputs from BMC Genomics
#5,674
of 10,614 outputs
Outputs of similar age
#96,249
of 163,178 outputs
Outputs of similar age from BMC Genomics
#33
of 70 outputs
Altmetric has tracked 22,664,644 research outputs across all sources so far. This one is in the 35th percentile – i.e., 35% of other outputs scored the same or lower than it.
So far Altmetric has tracked 10,614 research outputs from this source. They receive a mean Attention Score of 4.7. This one is in the 42nd percentile – i.e., 42% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 163,178 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 38th percentile – i.e., 38% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 70 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 50% of its contemporaries.