You are seeing a free-to-access but limited selection of the activity Altmetric has collected about this research output.
Click here to find out more.
X Demographics
Mendeley readers
Attention Score in Context
| Title |
Genetics of longevity. Data from the studies on Sicilian centenarians
|
|---|---|
| Published in |
Immunity & Ageing, April 2012
|
| DOI | 10.1186/1742-4933-9-8 |
| Pubmed ID | |
| Authors |
Carmela R Balistreri, Giuseppina Candore, Giulia Accardi, Manuela Bova, Silvio Buffa, Matteo Bulati, Giusi I Forte, Florinda Listì, Adriana Martorana, Marisa Palmeri, Maria Valeria Pellicanò, Loredana Vaccarino, Letizia Scola, Domenico Lio, Giuseppina Colonna-Romano |
| Abstract |
The demographic and social changes of the past decades have determined improvements in public health and longevity. So, the number of centenarians is increasing as a worldwide phenomenon. Scientists have focused their attention on centenarians as optimal model to address the biological mechanisms of "successful and unsuccessful ageing". They are equipped to reach the extreme limits of human life span and, most importantly, to show relatively good health, being able to perform their routine daily life and to escape fatal age-related diseases, such as cardiovascular diseases and cancer. Thus, particular attention has been centered on their genetic background and immune system. In this review, we report our data gathered for over 10 years in Sicilian centenarians. Based on results obtained, we suggest longevity as the result of an optimal performance of immune system and an over-expression of anti-inflammatory sequence variants of immune/inflammatory genes. However, as well known, genetic, epigenetic, stochastic and environmental factors seem to have a crucial role in ageing and longevity. Epigenetics is associated with ageing, as demonstrated in many studies. In particular, ageing is associated with a global loss of methylation state. Thus, the aim of future studies will be to analyze the weight of epigenetic changes in ageing and longevity. |
X Demographics
The data shown below were collected from the profiles of 3 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 1 | 33% |
| Unknown | 2 | 67% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 3 | 100% |
Mendeley readers
The data shown below were compiled from readership statistics for 57 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United Kingdom | 2 | 4% |
| Netherlands | 1 | 2% |
| India | 1 | 2% |
| Unknown | 53 | 93% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Researcher | 11 | 19% |
| Student > Ph. D. Student | 8 | 14% |
| Student > Bachelor | 8 | 14% |
| Student > Postgraduate | 4 | 7% |
| Professor > Associate Professor | 4 | 7% |
| Other | 13 | 23% |
| Unknown | 9 | 16% |
| Readers by discipline | Count | As % |
|---|---|---|
| Agricultural and Biological Sciences | 16 | 28% |
| Biochemistry, Genetics and Molecular Biology | 9 | 16% |
| Medicine and Dentistry | 7 | 12% |
| Psychology | 4 | 7% |
| Immunology and Microbiology | 2 | 4% |
| Other | 8 | 14% |
| Unknown | 11 | 19% |
Attention Score in Context
This research output has an Altmetric Attention Score of 13. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 25 April 2023.
All research outputs
#2,555,862
of 23,585,652 outputs
Outputs from Immunity & Ageing
#71
of 386 outputs
Outputs of similar age
#16,368
of 164,645 outputs
Outputs of similar age from Immunity & Ageing
#5
of 8 outputs
Altmetric has tracked 23,585,652 research outputs across all sources so far. Compared to these this one has done well and is in the 89th percentile: it's in the top 25% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 386 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 12.3. This one has done well, scoring higher than 81% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 164,645 tracked outputs that were published within six weeks on either side of this one in any source. This one has done particularly well, scoring higher than 90% of its contemporaries.
We're also able to compare this research output to 8 others from the same source and published within six weeks on either side of this one. This one has scored higher than 3 of them.