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Canalization of the evolutionary trajectory of the human influenza virus

Overview of attention for article published in BMC Biology, April 2012
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3 news outlets
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2 blogs
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5 X users
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1 Facebook page
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1 Wikipedia page

Citations

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Title
Canalization of the evolutionary trajectory of the human influenza virus
Published in
BMC Biology, April 2012
DOI 10.1186/1741-7007-10-38
Pubmed ID
Authors

Trevor Bedford, Andrew Rambaut, Mercedes Pascual

Abstract

Since its emergence in 1968, influenza A (H3N2) has evolved extensively in genotype and antigenic phenotype. However, despite strong pressure to evolve away from human immunity and to diversify in antigenic phenotype, H3N2 influenza shows paradoxically limited genetic and antigenic diversity present at any one time. Here, we propose a simple model of antigenic evolution in the influenza virus that accounts for this apparent discrepancy.

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Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 178 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United Kingdom 4 2%
United States 4 2%
Brazil 1 <1%
Israel 1 <1%
Mexico 1 <1%
Vietnam 1 <1%
Japan 1 <1%
Argentina 1 <1%
Unknown 164 92%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 51 29%
Researcher 49 28%
Student > Master 14 8%
Student > Bachelor 14 8%
Professor 12 7%
Other 24 13%
Unknown 14 8%
Readers by discipline Count As %
Agricultural and Biological Sciences 72 40%
Mathematics 13 7%
Computer Science 11 6%
Biochemistry, Genetics and Molecular Biology 10 6%
Immunology and Microbiology 10 6%
Other 32 18%
Unknown 30 17%