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Synergistic anti-proliferative effects of gambogic acid with docetaxel in gastrointestinal cancer cell lines

Overview of attention for article published in BMC Complementary Medicine and Therapies, April 2012
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Title
Synergistic anti-proliferative effects of gambogic acid with docetaxel in gastrointestinal cancer cell lines
Published in
BMC Complementary Medicine and Therapies, April 2012
DOI 10.1186/1472-6882-12-58
Pubmed ID
Authors

Zhengyun Zou, Li Xie, Jia Wei, Lixia Yu, Xiaoping Qian, Junhao Chen, Tingting Wang, Baorui Liu

Abstract

Gambogic acid has a marked anti-tumor effect for gastric and colorectal cancers in vitro and in vivo. However, recent investigations on gambogic acid have focused mainly on mono-drug therapy, and its potential role in cancer therapy has not been comprehensively illustrated. This study aimed to assess the interaction between gambogic acid and docetaxel on human gastrointestinal cancer cells and to investigate the mechanism of gambogic acid plus docetaxel treatment-induced apoptotic cell death.

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The data shown below were collected from the profiles of 2 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 17 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 17 100%

Demographic breakdown

Readers by professional status Count As %
Other 4 24%
Student > Master 4 24%
Student > Ph. D. Student 3 18%
Student > Bachelor 1 6%
Researcher 1 6%
Other 1 6%
Unknown 3 18%
Readers by discipline Count As %
Pharmacology, Toxicology and Pharmaceutical Science 4 24%
Agricultural and Biological Sciences 3 18%
Medicine and Dentistry 3 18%
Biochemistry, Genetics and Molecular Biology 1 6%
Chemistry 1 6%
Other 0 0%
Unknown 5 29%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 01 May 2012.
All research outputs
#15,243,120
of 22,664,644 outputs
Outputs from BMC Complementary Medicine and Therapies
#2,032
of 3,617 outputs
Outputs of similar age
#103,765
of 162,569 outputs
Outputs of similar age from BMC Complementary Medicine and Therapies
#72
of 131 outputs
Altmetric has tracked 22,664,644 research outputs across all sources so far. This one is in the 22nd percentile – i.e., 22% of other outputs scored the same or lower than it.
So far Altmetric has tracked 3,617 research outputs from this source. They typically receive more attention than average, with a mean Attention Score of 8.5. This one is in the 35th percentile – i.e., 35% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 162,569 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 25th percentile – i.e., 25% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 131 others from the same source and published within six weeks on either side of this one. This one is in the 28th percentile – i.e., 28% of its contemporaries scored the same or lower than it.