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Dietary L-arginine supplementation reduces Methotrexate-induced intestinal mucosal injury in rat

Overview of attention for article published in BMC Gastroenterology, April 2012
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Title
Dietary L-arginine supplementation reduces Methotrexate-induced intestinal mucosal injury in rat
Published in
BMC Gastroenterology, April 2012
DOI 10.1186/1471-230x-12-41
Pubmed ID
Authors

Tal Koppelmann, Yulia Pollak, Jorge Mogilner, Jacob Bejar, Arnold G Coran, Igor Sukhotnik

Abstract

Arginine (ARG) and nitric oxide maintain the mucosal integrity of the intestine in various intestinal disorders. In the present study, we evaluated the effects of oral ARG supplementation on intestinal structural changes, enterocyte proliferation and apoptosis following methotrexate (MTX)-induced intestinal damage in a rat.

Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 27 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 27 100%

Demographic breakdown

Readers by professional status Count As %
Student > Bachelor 5 19%
Student > Master 5 19%
Student > Doctoral Student 3 11%
Professor > Associate Professor 3 11%
Student > Ph. D. Student 3 11%
Other 3 11%
Unknown 5 19%
Readers by discipline Count As %
Medicine and Dentistry 7 26%
Agricultural and Biological Sciences 5 19%
Biochemistry, Genetics and Molecular Biology 3 11%
Nursing and Health Professions 2 7%
Veterinary Science and Veterinary Medicine 2 7%
Other 2 7%
Unknown 6 22%