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Creating and analyzing pathway and protein interaction compendia for modelling signal transduction networks

Overview of attention for article published in BMC Systems Biology, May 2012
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  • Above-average Attention Score compared to outputs of the same age and source (62nd percentile)

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Citations

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72 Dimensions

Readers on

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225 Mendeley
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8 CiteULike
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Title
Creating and analyzing pathway and protein interaction compendia for modelling signal transduction networks
Published in
BMC Systems Biology, May 2012
DOI 10.1186/1752-0509-6-29
Pubmed ID
Authors

Daniel C Kirouac, Julio Saez-Rodriguez, Jennifer Swantek, John M Burke, Douglas A Lauffenburger, Peter K Sorger

Abstract

Understanding the information-processing capabilities of signal transduction networks, how those networks are disrupted in disease, and rationally designing therapies to manipulate diseased states require systematic and accurate reconstruction of network topology. Data on networks central to human physiology, such as the inflammatory signalling networks analyzed here, are found in a multiplicity of on-line resources of pathway and interactome databases (Cancer CellMap, GeneGo, KEGG, NCI-Pathway Interactome Database (NCI-PID), PANTHER, Reactome, I2D, and STRING). We sought to determine whether these databases contain overlapping information and whether they can be used to construct high reliability prior knowledge networks for subsequent modeling of experimental data.

X Demographics

X Demographics

The data shown below were collected from the profiles of 5 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 225 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United States 9 4%
Germany 3 1%
France 2 <1%
Spain 2 <1%
Italy 2 <1%
Netherlands 1 <1%
Latvia 1 <1%
United Kingdom 1 <1%
Turkey 1 <1%
Other 4 2%
Unknown 199 88%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 65 29%
Researcher 60 27%
Professor > Associate Professor 15 7%
Student > Master 15 7%
Other 12 5%
Other 45 20%
Unknown 13 6%
Readers by discipline Count As %
Agricultural and Biological Sciences 106 47%
Biochemistry, Genetics and Molecular Biology 37 16%
Computer Science 18 8%
Engineering 13 6%
Medicine and Dentistry 11 5%
Other 19 8%
Unknown 21 9%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 3. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 10 August 2019.
All research outputs
#8,034,837
of 24,155,398 outputs
Outputs from BMC Systems Biology
#321
of 1,134 outputs
Outputs of similar age
#55,980
of 166,689 outputs
Outputs of similar age from BMC Systems Biology
#8
of 24 outputs
Altmetric has tracked 24,155,398 research outputs across all sources so far. This one is in the 44th percentile – i.e., 44% of other outputs scored the same or lower than it.
So far Altmetric has tracked 1,134 research outputs from this source. They receive a mean Attention Score of 3.7. This one has gotten more attention than average, scoring higher than 63% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 166,689 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 45th percentile – i.e., 45% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 24 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 62% of its contemporaries.