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Analysis of cell identity, morphology, apoptosis and mitotic activity in a primary neural cell culture system in Drosophila

Overview of attention for article published in Neural Development, May 2012
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Title
Analysis of cell identity, morphology, apoptosis and mitotic activity in a primary neural cell culture system in Drosophila
Published in
Neural Development, May 2012
DOI 10.1186/1749-8104-7-14
Pubmed ID
Authors

Manuela M Moraru, Boris Egger, Diarra B Bao, Simon G Sprecher

Abstract

In Drosophila, most neurogenetic research is carried out in vivo. Mammalian research demonstrates that primary cell culture techniques provide a powerful model to address cell autonomous and non-autonomous processes outside their endogenous environment. We developed a cell culture system in Drosophila using wildtype and genetically manipulated primary neural tissue for long-term observations. We assessed the molecular identity of distinct neural cell types by immunolabeling and genetically expressed fluorescent cell markers. We monitored mitotic activity of cell cultures derived from wildtype and tumorous larval brains. Our system provides a powerful approach to unveil developmental processes in the nervous system and to complement studies in vivo.

X Demographics

X Demographics

The data shown below were collected from the profiles of 2 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 81 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United Kingdom 1 1%
Turkey 1 1%
Greece 1 1%
Switzerland 1 1%
Unknown 77 95%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 27 33%
Researcher 15 19%
Student > Master 13 16%
Student > Postgraduate 4 5%
Other 3 4%
Other 10 12%
Unknown 9 11%
Readers by discipline Count As %
Agricultural and Biological Sciences 40 49%
Biochemistry, Genetics and Molecular Biology 13 16%
Neuroscience 10 12%
Immunology and Microbiology 2 2%
Linguistics 1 1%
Other 7 9%
Unknown 8 10%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 2. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 06 February 2016.
All research outputs
#14,143,926
of 22,664,644 outputs
Outputs from Neural Development
#107
of 226 outputs
Outputs of similar age
#96,363
of 163,491 outputs
Outputs of similar age from Neural Development
#1
of 8 outputs
Altmetric has tracked 22,664,644 research outputs across all sources so far. This one is in the 35th percentile – i.e., 35% of other outputs scored the same or lower than it.
So far Altmetric has tracked 226 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 6.1. This one is in the 48th percentile – i.e., 48% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 163,491 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 38th percentile – i.e., 38% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 8 others from the same source and published within six weeks on either side of this one. This one has scored higher than all of them