Title |
Macondo crude oil from the Deepwater Horizon oil spill disrupts specific developmental processes during zebrafish embryogenesis
|
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Published in |
BMC Biology, May 2012
|
DOI | 10.1186/1741-7007-10-40 |
Pubmed ID | |
Authors |
T Yvanka de Soysa, Allison Ulrich, Timo Friedrich, Danielle Pite, Shannon L Compton, Deborah Ok, Rebecca L Bernardos, Gerald B Downes, Shizuka Hsieh, Rachael Stein, M Caterina Lagdameo, Katherine Halvorsen, Lydia-Rose Kesich, Michael JF Barresi |
Abstract |
The Deepwater Horizon disaster was the largest marine oil spill in history, and total vertical exposure of oil to the water column suggests it could impact an enormous diversity of ecosystems. The most vulnerable organisms are those encountering these pollutants during their early life stages. Water-soluble components of crude oil and specific polycyclic aromatic hydrocarbons have been shown to cause defects in cardiovascular and craniofacial development in a variety of teleost species, but the developmental origins of these defects have yet to be determined. We have adopted zebrafish, Danio rerio, as a model to test whether water accumulated fractions (WAF) of the Deepwater Horizon oil could impact specific embryonic developmental processes. While not a native species to the Gulf waters, the developmental biology of zebrafish has been well characterized and makes it a powerful model system to reveal the cellular and molecular mechanisms behind Macondo crude toxicity. |
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Geographical breakdown
Country | Count | As % |
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United States | 6 | 50% |
Mexico | 1 | 8% |
Canada | 1 | 8% |
Unknown | 4 | 33% |
Demographic breakdown
Type | Count | As % |
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Members of the public | 7 | 58% |
Scientists | 3 | 25% |
Practitioners (doctors, other healthcare professionals) | 1 | 8% |
Science communicators (journalists, bloggers, editors) | 1 | 8% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
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United States | 2 | 2% |
Germany | 1 | <1% |
Brazil | 1 | <1% |
Canada | 1 | <1% |
United Kingdom | 1 | <1% |
Argentina | 1 | <1% |
Mexico | 1 | <1% |
Unknown | 120 | 94% |
Demographic breakdown
Readers by professional status | Count | As % |
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Student > Master | 24 | 19% |
Researcher | 21 | 16% |
Student > Ph. D. Student | 19 | 15% |
Student > Bachelor | 15 | 12% |
Student > Doctoral Student | 7 | 5% |
Other | 21 | 16% |
Unknown | 21 | 16% |
Readers by discipline | Count | As % |
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Agricultural and Biological Sciences | 50 | 39% |
Environmental Science | 23 | 18% |
Biochemistry, Genetics and Molecular Biology | 9 | 7% |
Medicine and Dentistry | 7 | 5% |
Engineering | 4 | 3% |
Other | 10 | 8% |
Unknown | 25 | 20% |