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Macondo crude oil from the Deepwater Horizon oil spill disrupts specific developmental processes during zebrafish embryogenesis

Overview of attention for article published in BMC Biology, May 2012
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Title
Macondo crude oil from the Deepwater Horizon oil spill disrupts specific developmental processes during zebrafish embryogenesis
Published in
BMC Biology, May 2012
DOI 10.1186/1741-7007-10-40
Pubmed ID
Authors

T Yvanka de Soysa, Allison Ulrich, Timo Friedrich, Danielle Pite, Shannon L Compton, Deborah Ok, Rebecca L Bernardos, Gerald B Downes, Shizuka Hsieh, Rachael Stein, M Caterina Lagdameo, Katherine Halvorsen, Lydia-Rose Kesich, Michael JF Barresi

Abstract

The Deepwater Horizon disaster was the largest marine oil spill in history, and total vertical exposure of oil to the water column suggests it could impact an enormous diversity of ecosystems. The most vulnerable organisms are those encountering these pollutants during their early life stages. Water-soluble components of crude oil and specific polycyclic aromatic hydrocarbons have been shown to cause defects in cardiovascular and craniofacial development in a variety of teleost species, but the developmental origins of these defects have yet to be determined. We have adopted zebrafish, Danio rerio, as a model to test whether water accumulated fractions (WAF) of the Deepwater Horizon oil could impact specific embryonic developmental processes. While not a native species to the Gulf waters, the developmental biology of zebrafish has been well characterized and makes it a powerful model system to reveal the cellular and molecular mechanisms behind Macondo crude toxicity.

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Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 128 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United States 2 2%
Germany 1 <1%
Brazil 1 <1%
Canada 1 <1%
United Kingdom 1 <1%
Argentina 1 <1%
Mexico 1 <1%
Unknown 120 94%

Demographic breakdown

Readers by professional status Count As %
Student > Master 24 19%
Researcher 21 16%
Student > Ph. D. Student 19 15%
Student > Bachelor 15 12%
Student > Doctoral Student 7 5%
Other 21 16%
Unknown 21 16%
Readers by discipline Count As %
Agricultural and Biological Sciences 50 39%
Environmental Science 23 18%
Biochemistry, Genetics and Molecular Biology 9 7%
Medicine and Dentistry 7 5%
Engineering 4 3%
Other 10 8%
Unknown 25 20%