FcγRIIIa receptor polymorphism influences NK cell mediated ADCC activity against HIV

RT @FOHMaster: @drakchaurasia @rkvweb @muglikar_ And NK cells comprise a significant share of innate immunity via antibody dependent cellul…

@drakchaurasia @rkvweb @muglikar_ And NK cells comprise a significant share of innate immunity via antibody dependent cellular cytotoxicity. Interesting how they are activated by FcγRIIIa yet IgG4 exhibits minimal binding to that receptor. 🤔 https://t.co/

@NoyesJHumphrey 👇

@GVDBossche “HIV-specific ADCC is important in HIV control & resistance. The ADCC is mediated primarily by natural killer cell activated through the binding of FcγRIIIa receptor to the Fc portion of antibody bound to the antigen expressed on the infect