Title |
Ultra-protective ventilation and hypoxemia
|
---|---|
Published in |
Critical Care, May 2016
|
DOI | 10.1186/s13054-016-1310-9 |
Pubmed ID | |
Authors |
Luciano Gattinoni |
Abstract |
Partial extracorporeal CO2 removal allows a decreasing tidal volume without respiratory acidosis in patients with acute respiratory distress syndrome. This, however, may be associated with worsening hypoxemia, due to several mechanisms, such as gravitational and reabsorption atelectasis, due to a decrease in mean airway pressure and a critically low ventilation-perfusion ratio, respectively. In addition, an imbalance between alveolar and artificial lung partial pressures of nitrogen may accelerate the process. Finally, the decrease in the respiratory quotient, leading to unrecognized alveolar hypoxia and monotonous low plateau pressures preventing critical opening, may contribute to hypoxemia. |
X Demographics
Geographical breakdown
Country | Count | As % |
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United Kingdom | 5 | 18% |
United States | 3 | 11% |
Brazil | 2 | 7% |
Venezuela, Bolivarian Republic of | 1 | 4% |
Chile | 1 | 4% |
Spain | 1 | 4% |
South Africa | 1 | 4% |
Unknown | 14 | 50% |
Demographic breakdown
Type | Count | As % |
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Members of the public | 18 | 64% |
Practitioners (doctors, other healthcare professionals) | 7 | 25% |
Scientists | 2 | 7% |
Science communicators (journalists, bloggers, editors) | 1 | 4% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
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Czechia | 1 | 1% |
Unknown | 71 | 99% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Researcher | 14 | 19% |
Other | 8 | 11% |
Student > Master | 6 | 8% |
Student > Doctoral Student | 6 | 8% |
Student > Ph. D. Student | 5 | 7% |
Other | 20 | 28% |
Unknown | 13 | 18% |
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---|---|---|
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Nursing and Health Professions | 3 | 4% |
Agricultural and Biological Sciences | 1 | 1% |
Design | 1 | 1% |
Unknown | 16 | 22% |