@thomaschattwiII @halvorz Lysosomal impairments also increase secretion of tau protein, the other major AD plaque component: https://t.co/ZWXXmEVB3Q It is a matter of impaired autophagy: https://t.co/Y55DG8Wjdq Healthy lysosomes prevent such garbage fr
Promoting tau secretion and propagation by hyperactive p300/CBP via autophagy-lysosomal pathway in tauopathy. Findings suggest that inhibition of p300/CBP as a novel approach to correct ALP dysfunction and block disease progression in tauopathy. https://t.
RT @LysosomeJC: Promoting tau secretion and propagation by hyperactive p300/CBP via autophagy-lysosomal pathway in tauopathy https://t.co/f…
RT @LysosomeJC: Promoting tau secretion and propagation by hyperactive p300/CBP via autophagy-lysosomal pathway in tauopathy https://t.co/f…