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Effect of virtual reality exposure therapy on social participation in people with a psychotic disorder (VRETp): study protocol for a randomized controlled trial

Overview of attention for article published in Trials, January 2016
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Title
Effect of virtual reality exposure therapy on social participation in people with a psychotic disorder (VRETp): study protocol for a randomized controlled trial
Published in
Trials, January 2016
DOI 10.1186/s13063-015-1140-0
Pubmed ID
Authors

Roos Pot-Kolder, Wim Veling, Chris Geraets, Mark van der Gaag

Abstract

Many patients with a psychotic disorder participate poorly in society. When psychotic disorders are in partial remission, feelings of paranoia, delusions of reference, social anxiety and self-stigmatization often remain at diminished severity and may lead to avoidance of places and people. Virtual reality exposure therapy (VRET) is an evidence-based treatment for several anxiety disorders. For patients with a psychotic disorder, the VRETp was developed to help them experience exposure to feared social situations. The present study aims to investigate the effects of VRETp on social participation in real life among patients with a psychotic disorder. The study is a single-blind randomized controlled trial with two conditions: the active condition, in which participants receive the virtual reality treatment together with treatment as usual (TAU), and the waiting list condition, in which participants receive TAU only. The two groups are compared at baseline, at 3 months posttreatment and at 6 months follow-up. All participants on the waiting list are also offered the virtual reality treatment after the follow-up measurements are completed. The primary outcome is social participation. Secondary outcomes are quality of life, interaction anxiety, depression and social functioning in general. Moderator and mediator analyses are conducted with stigma, cognitive schemata, cognitive biases, medication adherence, simulator sickness and presence in virtual reality. If effective, a cost-effectiveness analysis will be conducted. Results from the posttreatment measurement can be considered strong empirical indicators of the effectiveness of VRETp. The 6-month follow-up data may provide reliable documentation of the long-term effects of the treatment on the outcome variables. Data from pre-treatment and mid-treatment can be used to reveal possible pathways of change. Current Controlled Trials: ISRCTN12929657 . Date of registration: 8 September 2015.

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Geographical breakdown

Country Count As %
Portugal 1 <1%
Colombia 1 <1%
Brazil 1 <1%
Canada 1 <1%
Spain 1 <1%
Unknown 282 98%

Demographic breakdown

Readers by professional status Count As %
Student > Master 57 20%
Researcher 32 11%
Student > Ph. D. Student 28 10%
Student > Bachelor 27 9%
Student > Doctoral Student 22 8%
Other 48 17%
Unknown 73 25%
Readers by discipline Count As %
Psychology 90 31%
Medicine and Dentistry 31 11%
Nursing and Health Professions 23 8%
Computer Science 12 4%
Neuroscience 10 3%
Other 27 9%
Unknown 94 33%