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Downregulation of the tumor-suppressor miR-16 via progestin-mediated oncogenic signaling contributes to breast cancer development

Overview of attention for article published in Breast Cancer Research, May 2012
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About this Attention Score

  • In the top 25% of all research outputs scored by Altmetric
  • High Attention Score compared to outputs of the same age (88th percentile)
  • High Attention Score compared to outputs of the same age and source (99th percentile)

Mentioned by

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4 X users
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2 patents
wikipedia
2 Wikipedia pages

Citations

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96 Dimensions

Readers on

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85 Mendeley
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Title
Downregulation of the tumor-suppressor miR-16 via progestin-mediated oncogenic signaling contributes to breast cancer development
Published in
Breast Cancer Research, May 2012
DOI 10.1186/bcr3187
Pubmed ID
Authors

Martin A Rivas, Leandro Venturutti, Yi-Wen Huang, Roxana Schillaci, Tim Hui-Ming Huang, Patricia V Elizalde

Abstract

Experimental and clinical evidence points to a critical role of progesterone and the nuclear progesterone receptor (PR) in controlling mammary gland tumorigenesis. However, the molecular mechanisms of progesterone action in breast cancer still remain elusive. On the other hand, micro RNAs (miRNAs) are short ribonucleic acids which have also been found to play a pivotal role in cancer pathogenesis. The role of miRNA in progestin-induced breast cancer is poorly explored. In this study we explored progestin modulation of miRNA expression in mammary tumorigenesis.

X Demographics

X Demographics

The data shown below were collected from the profiles of 4 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 85 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United States 1 1%
Belgium 1 1%
Egypt 1 1%
Unknown 82 96%

Demographic breakdown

Readers by professional status Count As %
Researcher 22 26%
Student > Ph. D. Student 14 16%
Student > Master 10 12%
Student > Doctoral Student 6 7%
Student > Bachelor 6 7%
Other 14 16%
Unknown 13 15%
Readers by discipline Count As %
Agricultural and Biological Sciences 24 28%
Biochemistry, Genetics and Molecular Biology 21 25%
Medicine and Dentistry 17 20%
Chemistry 2 2%
Neuroscience 2 2%
Other 4 5%
Unknown 15 18%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 12. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 02 March 2023.
All research outputs
#3,084,534
of 25,397,764 outputs
Outputs from Breast Cancer Research
#320
of 2,056 outputs
Outputs of similar age
#19,406
of 176,597 outputs
Outputs of similar age from Breast Cancer Research
#1
of 34 outputs
Altmetric has tracked 25,397,764 research outputs across all sources so far. Compared to these this one has done well and is in the 87th percentile: it's in the top 25% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 2,056 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 12.1. This one has done well, scoring higher than 84% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 176,597 tracked outputs that were published within six weeks on either side of this one in any source. This one has done well, scoring higher than 88% of its contemporaries.
We're also able to compare this research output to 34 others from the same source and published within six weeks on either side of this one. This one has done particularly well, scoring higher than 99% of its contemporaries.