Title |
Nutritional regulation of muscle protein synthesis with resistance exercise: strategies to enhance anabolism
|
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Published in |
Nutrition & Metabolism, May 2012
|
DOI | 10.1186/1743-7075-9-40 |
Pubmed ID | |
Authors |
Tyler A Churchward-Venne, Nicholas A Burd, Stuart M Phillips |
Abstract |
Provision of dietary amino acids increases skeletal muscle protein synthesis (MPS), an effect that is enhanced by prior resistance exercise. As a fundamentally necessary process in the enhancement of muscle mass, strategies to enhance rates of MPS would be beneficial in the development of interventions aimed at increasing skeletal muscle mass particularly when combined with chronic resistance exercise. The purpose of this review article is to provide an update on current findings regarding the nutritional regulation of MPS and highlight nutrition based strategies that may serve to maximize skeletal muscle protein anabolism with resistance exercise. Such factors include timing of protein intake, dietary protein type, the role of leucine as a key anabolic amino acid, and the impact of other macronutrients (i.e. carbohydrate) on the regulation of MPS after resistance exercise. We contend that nutritional strategies that serve to maximally stimulate MPS may be useful in the development of nutrition and exercise based interventions aimed at enhancing skeletal muscle mass which may be of interest to elderly populations and to athletes. |
X Demographics
Geographical breakdown
Country | Count | As % |
---|---|---|
United Kingdom | 33 | 21% |
United States | 32 | 20% |
Canada | 12 | 8% |
Australia | 8 | 5% |
Spain | 5 | 3% |
Japan | 3 | 2% |
Netherlands | 3 | 2% |
Austria | 2 | 1% |
New Zealand | 2 | 1% |
Other | 18 | 11% |
Unknown | 39 | 25% |
Demographic breakdown
Type | Count | As % |
---|---|---|
Members of the public | 100 | 64% |
Scientists | 28 | 18% |
Practitioners (doctors, other healthcare professionals) | 27 | 17% |
Science communicators (journalists, bloggers, editors) | 1 | <1% |
Unknown | 1 | <1% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
Brazil | 5 | 1% |
United Kingdom | 4 | <1% |
United States | 2 | <1% |
Spain | 2 | <1% |
Australia | 1 | <1% |
France | 1 | <1% |
Indonesia | 1 | <1% |
Netherlands | 1 | <1% |
Denmark | 1 | <1% |
Other | 2 | <1% |
Unknown | 457 | 96% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Bachelor | 103 | 22% |
Student > Master | 94 | 20% |
Researcher | 42 | 9% |
Student > Ph. D. Student | 40 | 8% |
Other | 38 | 8% |
Other | 95 | 20% |
Unknown | 65 | 14% |
Readers by discipline | Count | As % |
---|---|---|
Sports and Recreations | 148 | 31% |
Medicine and Dentistry | 78 | 16% |
Agricultural and Biological Sciences | 77 | 16% |
Nursing and Health Professions | 40 | 8% |
Biochemistry, Genetics and Molecular Biology | 31 | 6% |
Other | 28 | 6% |
Unknown | 75 | 16% |