Acute myeloid leukemia with inv(16)(p13.1q22) and deletion of the 5’MYH11/3’CBFB gene fusion: a report of two cases and literature review. Mapping w/ SNP-microarray confirmed that recurrent deletions of the 3’-flanking CBFb region include 16q22 CTCF TSG. h
Indeed, a widely expressed transcription factor with multiple DNA sequence specificity, CTCF, is localized at chromosome segment 16q22.1 within one of the smallest regions of overlap for common deletions in breast and prostate cancers https://t.co/viWtv7H3
AML with inv(16)(p13.1q22) and deletion of the 5’MYH11/3’CBFB gene fusion: a report of new cases and literature review. CTCF is one of the main cancer-related TSG-like genes found in the center of recurrently deleted overlapping regions in 16q chromosome.
New article: Acute myeloid leukemia with inv(16)(p13.1q22) and deletion of the 5'MYH11/3'CBFB gene fusion: a report of two cases and literature review. https://t.co/omj8kvsOcu #AML #leusm #hematology