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Mendeley readers
Title |
Cofactor-mediated conformational control in the bifunctional kinase/RNase Ire1
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Published in |
BMC Biology, July 2011
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DOI | 10.1186/1741-7007-9-48 |
Pubmed ID | |
Authors |
Alexei V Korennykh, Pascal F Egea, Andrei A Korostelev, Janet Finer-Moore, Robert M Stroud, Chao Zhang, Kevan M Shokat, Peter Walter |
Abstract |
Ire1 is a signal transduction protein in the endoplasmic reticulum (ER) membrane that serves to adjust the protein-folding capacity of the ER according to the needs of the cell. Ire1 signals, in a transcriptional program, the unfolded protein response (UPR) via the coordinated action of its protein kinase and RNase domains. In this study, we investigated how the binding of cofactors to the kinase domain of Ire1 modulates its RNase activity. |
X Demographics
The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
Country | Count | As % |
---|---|---|
United States | 1 | 100% |
Demographic breakdown
Type | Count | As % |
---|---|---|
Scientists | 1 | 100% |
Mendeley readers
The data shown below were compiled from readership statistics for 85 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
Country | Count | As % |
---|---|---|
United States | 2 | 2% |
Singapore | 1 | 1% |
Unknown | 82 | 96% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Ph. D. Student | 21 | 25% |
Researcher | 17 | 20% |
Student > Bachelor | 9 | 11% |
Professor | 7 | 8% |
Professor > Associate Professor | 7 | 8% |
Other | 21 | 25% |
Unknown | 3 | 4% |
Readers by discipline | Count | As % |
---|---|---|
Agricultural and Biological Sciences | 44 | 52% |
Biochemistry, Genetics and Molecular Biology | 25 | 29% |
Chemistry | 8 | 9% |
Medicine and Dentistry | 2 | 2% |
Physics and Astronomy | 1 | 1% |
Other | 2 | 2% |
Unknown | 3 | 4% |