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X Demographics
Mendeley readers
Attention Score in Context
| Title |
Is venous congestion associated with reduced cerebral oxygenation and worse neurological outcome after cardiac arrest?
|
|---|---|
| Published in |
Critical Care, May 2016
|
| DOI | 10.1186/s13054-016-1297-2 |
| Pubmed ID | |
| Authors |
Koen Ameloot, Cornelia Genbrugge, Ingrid Meex, Ward Eertmans, Frank Jans, Cathy De Deyne, Joseph Dens, Wilfried Mullens, Bert Ferdinande, Matthias Dupont |
| Abstract |
Post-cardiac arrest (CA) patients are at risk of secondary ischemic damage in the case of suboptimal brain oxygenation during an ICU stay. We hypothesized that elevated central venous pressures (CVP) would impair cerebral perfusion and oxygenation (venous cerebral congestion). The aim of the present study was to investigate the relationship between CVP, cerebral tissue oxygen saturation (SctO2) as assessed with near-infrared spectroscopy (NIRS) and outcome in post-CA patients. This was an observational study in 48 post-CA patients with continuous CVP and SctO2 monitoring during therapeutic hypothermia. The relationship between CVP and mean SctO2 was best described by an S-shaped, third-degree polynomial regression curve (SctO2 = -0.002 × CVP(3) + 0.08 × CVP(2) - 1.07 × CVP + 69.78 %, R (2) 0.89, n = 1,949,108 data points) with high CVP (>20 mmHg) being associated with cerebral desaturation. Multivariate linear regression revealed CVP to be a more important determinant of SctO2 than mean arterial pressure (MAP) without important interaction between both (SctO2 = 0.01 × MAP - 0.20 × CVP + 0.001 × MAP × CVP + 65.55 %). CVP and cardiac output were independent determinants of SctO2 with some interaction between both (SctO2 = 1.86 × CO - 0.09 × CVP - 0.05 × CO × CVP + 60.04 %). Logistic regression revealed that a higher percentage of time with CVP above 5 mmHg was associated with lower chance of survival with a good neurological outcome (cerebral performance category (CPC) 1-2) at 180 days (OR 0.96, 95 % CI 0.92-1.00, p = 0.04). In a multivariate model, the negative association between CVP and outcome persisted after correction for hemodynamic variables, including ejection fraction and MAP. Elevated CVP results in lower brain saturation and is associated with worse outcome in post-CA patients. This pilot study provides support that venous cerebral congestion as indicated by high CVP may be detrimental for post-CA patients. |
X Demographics
The data shown below were collected from the profiles of 80 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 11 | 14% |
| United Kingdom | 5 | 6% |
| Saudi Arabia | 4 | 5% |
| India | 2 | 3% |
| Spain | 2 | 3% |
| Turkey | 2 | 3% |
| Mexico | 2 | 3% |
| Canada | 2 | 3% |
| Sweden | 2 | 3% |
| Other | 17 | 21% |
| Unknown | 31 | 39% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 51 | 64% |
| Practitioners (doctors, other healthcare professionals) | 18 | 23% |
| Science communicators (journalists, bloggers, editors) | 6 | 8% |
| Scientists | 5 | 6% |
Mendeley readers
The data shown below were compiled from readership statistics for 78 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United Kingdom | 1 | 1% |
| Unknown | 77 | 99% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Researcher | 11 | 14% |
| Student > Ph. D. Student | 8 | 10% |
| Student > Bachelor | 8 | 10% |
| Other | 6 | 8% |
| Student > Master | 6 | 8% |
| Other | 21 | 27% |
| Unknown | 18 | 23% |
| Readers by discipline | Count | As % |
|---|---|---|
| Medicine and Dentistry | 39 | 50% |
| Nursing and Health Professions | 4 | 5% |
| Engineering | 3 | 4% |
| Psychology | 2 | 3% |
| Agricultural and Biological Sciences | 2 | 3% |
| Other | 6 | 8% |
| Unknown | 22 | 28% |
Attention Score in Context
This research output has an Altmetric Attention Score of 44. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 06 July 2022.
All research outputs
#950,115
of 25,632,496 outputs
Outputs from Critical Care
#722
of 6,595 outputs
Outputs of similar age
#17,028
of 333,919 outputs
Outputs of similar age from Critical Care
#17
of 111 outputs
Altmetric has tracked 25,632,496 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 96th percentile: it's in the top 5% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 6,595 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 20.7. This one has done well, scoring higher than 89% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 333,919 tracked outputs that were published within six weeks on either side of this one in any source. This one has done particularly well, scoring higher than 94% of its contemporaries.
We're also able to compare this research output to 111 others from the same source and published within six weeks on either side of this one. This one has done well, scoring higher than 84% of its contemporaries.