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18 β-glycyrrhetinic acid inhibits rotavirus replication in culture

Overview of attention for article published in Virology Journal, May 2012
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Title
18 β-glycyrrhetinic acid inhibits rotavirus replication in culture
Published in
Virology Journal, May 2012
DOI 10.1186/1743-422x-9-96
Pubmed ID
Authors

Michele E Hardy, Jay M Hendricks, Jeana M Paulson, Nicholas R Faunce

Abstract

Glycyrrhizin (GA) and primary metabolite 18β-glycyrrhetinic acid (GRA) are pharmacologically active components of the medicinal licorice root, and both have been shown to have antiviral and immunomodulatory properties. Although these properties are well established, the mechanisms of action are not completely understood. In this study, GA and GRA were tested for the ability to inhibit rotavirus replication in cell culture, toward a long term goal of discovering natural compounds that may complement existing vaccines.

X Demographics

X Demographics

The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 37 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United States 1 3%
Unknown 36 97%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 5 14%
Student > Master 4 11%
Student > Bachelor 4 11%
Student > Doctoral Student 3 8%
Professor > Associate Professor 3 8%
Other 9 24%
Unknown 9 24%
Readers by discipline Count As %
Agricultural and Biological Sciences 8 22%
Biochemistry, Genetics and Molecular Biology 6 16%
Pharmacology, Toxicology and Pharmaceutical Science 4 11%
Medicine and Dentistry 4 11%
Neuroscience 1 3%
Other 3 8%
Unknown 11 30%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 24 May 2012.
All research outputs
#18,306,425
of 22,665,794 outputs
Outputs from Virology Journal
#2,421
of 3,029 outputs
Outputs of similar age
#126,416
of 164,244 outputs
Outputs of similar age from Virology Journal
#23
of 46 outputs
Altmetric has tracked 22,665,794 research outputs across all sources so far. This one is in the 11th percentile – i.e., 11% of other outputs scored the same or lower than it.
So far Altmetric has tracked 3,029 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 25.5. This one is in the 5th percentile – i.e., 5% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 164,244 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 9th percentile – i.e., 9% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 46 others from the same source and published within six weeks on either side of this one. This one is in the 21st percentile – i.e., 21% of its contemporaries scored the same or lower than it.