Title |
Bench-to-bedside review: Rhabdomyolysis – an overview for clinicians
|
---|---|
Published in |
Critical Care, October 2004
|
DOI | 10.1186/cc2978 |
Pubmed ID | |
Authors |
Ana L Huerta-Alardín, Joseph Varon, Paul E Marik |
Abstract |
Rhabdomyolysis ranges from an asymptomatic illness with elevation in the creatine kinase level to a life-threatening condition associated with extreme elevations in creatine kinase, electrolyte imbalances, acute renal failure and disseminated intravascular coagulation. Muscular trauma is the most common cause of rhabdomyolysis. Less common causes include muscle enzyme deficiencies, electrolyte abnormalities, infectious causes, drugs, toxins and endocrinopathies. Weakness, myalgia and tea-colored urine are the main clinical manifestations. The most sensitive laboratory finding of muscle injury is an elevated plasma creatine kinase level. The management of patients with rhabdomyolysis includes early vigorous hydration. |
X Demographics
Geographical breakdown
Country | Count | As % |
---|---|---|
United States | 7 | 25% |
Mexico | 1 | 4% |
Egypt | 1 | 4% |
Switzerland | 1 | 4% |
India | 1 | 4% |
Argentina | 1 | 4% |
Saudi Arabia | 1 | 4% |
Costa Rica | 1 | 4% |
Spain | 1 | 4% |
Other | 1 | 4% |
Unknown | 12 | 43% |
Demographic breakdown
Type | Count | As % |
---|---|---|
Members of the public | 19 | 68% |
Practitioners (doctors, other healthcare professionals) | 6 | 21% |
Scientists | 3 | 11% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
Brazil | 5 | <1% |
United States | 4 | <1% |
Spain | 4 | <1% |
Japan | 3 | <1% |
Italy | 2 | <1% |
Turkey | 2 | <1% |
Russia | 2 | <1% |
Hong Kong | 1 | <1% |
Uruguay | 1 | <1% |
Other | 8 | 1% |
Unknown | 567 | 95% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Other | 96 | 16% |
Researcher | 82 | 14% |
Student > Postgraduate | 73 | 12% |
Student > Master | 56 | 9% |
Student > Bachelor | 56 | 9% |
Other | 144 | 24% |
Unknown | 92 | 15% |
Readers by discipline | Count | As % |
---|---|---|
Medicine and Dentistry | 339 | 57% |
Biochemistry, Genetics and Molecular Biology | 31 | 5% |
Nursing and Health Professions | 29 | 5% |
Agricultural and Biological Sciences | 24 | 4% |
Sports and Recreations | 14 | 2% |
Other | 52 | 9% |
Unknown | 110 | 18% |