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Wallerian degeneration: the innate-immune response to traumatic nerve injury

Overview of attention for article published in Journal of Neuroinflammation, August 2011
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  • Good Attention Score compared to outputs of the same age (73rd percentile)
  • Above-average Attention Score compared to outputs of the same age and source (63rd percentile)

Mentioned by

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3 X users
wikipedia
1 Wikipedia page

Citations

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376 Dimensions

Readers on

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517 Mendeley
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1 CiteULike
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Title
Wallerian degeneration: the innate-immune response to traumatic nerve injury
Published in
Journal of Neuroinflammation, August 2011
DOI 10.1186/1742-2094-8-109
Pubmed ID
Authors

Shlomo Rotshenker

Abstract

Traumatic injury to peripheral nerves results in the loss of neural functions. Recovery by regeneration depends on the cellular and molecular events of Wallerian degeneration that injury induces distal to the lesion site, the domain through which severed axons regenerate back to their target tissues. Innate-immunity is central to Wallerian degeneration since innate-immune cells, functions and molecules that are produced by immune and non-immune cells are involved. The innate-immune response helps to turn the peripheral nerve tissue into an environment that supports regeneration by removing inhibitory myelin and by upregulating neurotrophic properties. The characteristics of an efficient innate-immune response are rapid onset and conclusion, and the orchestrated interplay between Schwann cells, fibroblasts, macrophages, endothelial cells, and molecules they produce. Wallerian degeneration serves as a prelude for successful repair when these requirements are met. In contrast, functional recovery is poor when injury fails to produce the efficient innate-immune response of Wallerian degeneration.

X Demographics

X Demographics

The data shown below were collected from the profiles of 3 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 517 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United States 3 <1%
United Kingdom 2 <1%
Portugal 1 <1%
Brazil 1 <1%
Switzerland 1 <1%
Canada 1 <1%
Chile 1 <1%
Unknown 507 98%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 88 17%
Student > Bachelor 78 15%
Student > Master 59 11%
Researcher 50 10%
Student > Doctoral Student 38 7%
Other 85 16%
Unknown 119 23%
Readers by discipline Count As %
Medicine and Dentistry 100 19%
Agricultural and Biological Sciences 85 16%
Neuroscience 77 15%
Biochemistry, Genetics and Molecular Biology 46 9%
Engineering 21 4%
Other 56 11%
Unknown 132 26%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 6. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 09 December 2019.
All research outputs
#6,495,301
of 25,371,288 outputs
Outputs from Journal of Neuroinflammation
#1,162
of 2,951 outputs
Outputs of similar age
#36,005
of 135,477 outputs
Outputs of similar age from Journal of Neuroinflammation
#12
of 33 outputs
Altmetric has tracked 25,371,288 research outputs across all sources so far. This one has received more attention than most of these and is in the 74th percentile.
So far Altmetric has tracked 2,951 research outputs from this source. They typically receive more attention than average, with a mean Attention Score of 8.7. This one has gotten more attention than average, scoring higher than 60% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 135,477 tracked outputs that were published within six weeks on either side of this one in any source. This one has gotten more attention than average, scoring higher than 73% of its contemporaries.
We're also able to compare this research output to 33 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 63% of its contemporaries.