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Aging impairs contraction-induced human skeletal muscle mTORC1 signaling and protein synthesis

Overview of attention for article published in Skeletal Muscle, March 2011
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About this Attention Score

  • In the top 25% of all research outputs scored by Altmetric
  • Among the highest-scoring outputs from this source (#38 of 372)
  • High Attention Score compared to outputs of the same age (92nd percentile)
  • High Attention Score compared to outputs of the same age and source (99th percentile)

Mentioned by

blogs
1 blog
twitter
13 X users
patent
2 patents

Citations

dimensions_citation
297 Dimensions

Readers on

mendeley
290 Mendeley
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Title
Aging impairs contraction-induced human skeletal muscle mTORC1 signaling and protein synthesis
Published in
Skeletal Muscle, March 2011
DOI 10.1186/2044-5040-1-11
Pubmed ID
Authors

Christopher S Fry, Micah J Drummond, Erin L Glynn, Jared M Dickinson, David M Gundermann, Kyle L Timmerman, Dillon K Walker, Shaheen Dhanani, Elena Volpi, Blake B Rasmussen

Abstract

Sarcopenia, the loss of skeletal muscle mass during aging, increases the risk for falls and dependency. Resistance exercise (RE) training is an effective treatment to improve muscle mass and strength in older adults, but aging is associated with a smaller amount of training-induced hypertrophy. This may be due in part to an inability to stimulate muscle-protein synthesis (MPS) after an acute bout of RE. We hypothesized that older adults would have impaired mammalian target of rapamycin complex (mTORC)1 signaling and MPS response compared with young adults after acute RE.

X Demographics

X Demographics

The data shown below were collected from the profiles of 13 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 290 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United States 4 1%
United Kingdom 3 1%
Japan 1 <1%
Brazil 1 <1%
Unknown 281 97%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 57 20%
Student > Master 49 17%
Researcher 33 11%
Student > Bachelor 25 9%
Professor 13 4%
Other 50 17%
Unknown 63 22%
Readers by discipline Count As %
Biochemistry, Genetics and Molecular Biology 54 19%
Agricultural and Biological Sciences 41 14%
Medicine and Dentistry 41 14%
Sports and Recreations 40 14%
Nursing and Health Professions 17 6%
Other 22 8%
Unknown 75 26%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 18. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 25 May 2023.
All research outputs
#1,888,497
of 23,839,820 outputs
Outputs from Skeletal Muscle
#38
of 372 outputs
Outputs of similar age
#7,824
of 110,825 outputs
Outputs of similar age from Skeletal Muscle
#1
of 6 outputs
Altmetric has tracked 23,839,820 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 92nd percentile: it's in the top 10% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 372 research outputs from this source. They typically receive more attention than average, with a mean Attention Score of 8.2. This one has done particularly well, scoring higher than 90% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 110,825 tracked outputs that were published within six weeks on either side of this one in any source. This one has done particularly well, scoring higher than 92% of its contemporaries.
We're also able to compare this research output to 6 others from the same source and published within six weeks on either side of this one. This one has scored higher than all of them