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Mendeley readers
| Title |
Protective role of 1,25(OH)2vitamin D3 in the mucosal injury and epithelial barrier disruption in DSS-induced acute colitis in mice
|
|---|---|
| Published in |
BMC Gastroenterology, May 2012
|
| DOI | 10.1186/1471-230x-12-57 |
| Pubmed ID | |
| Authors |
Hongwei Zhao, Hong Zhang, Hui Wu, Hui Li, Lei Liu, Jian Guo, Chenyang Li, David Q Shih, Xiaolan Zhang |
| Abstract |
Intestinal hyper-permeability plays a critical role in the etiopathogenesis of inflammatory bowel disease (IBD) by affecting the penetration of pathogens, toxic compounds and macromolecules. 1,25-dihydroxyvitamin D3 [1,25(OH)2D3], the active form of vitamin D, has been shown to be an important regulator of IBD and recent epidemiology suggests that patients with IBD have an impaired vitamin D status. The purpose of this study is to investigate the possible protective effects of 1,25(OH)2D3 on mucosal injury and epithelial barrier disruption on dextran sulfate sodium (DSS)-induced acute colitis model. |
Mendeley readers
The data shown below were compiled from readership statistics for 201 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 2 | <1% |
| Spain | 1 | <1% |
| Austria | 1 | <1% |
| Unknown | 197 | 98% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Ph. D. Student | 33 | 16% |
| Student > Bachelor | 27 | 13% |
| Student > Master | 26 | 13% |
| Researcher | 25 | 12% |
| Professor > Associate Professor | 12 | 6% |
| Other | 33 | 16% |
| Unknown | 45 | 22% |
| Readers by discipline | Count | As % |
|---|---|---|
| Agricultural and Biological Sciences | 53 | 26% |
| Medicine and Dentistry | 42 | 21% |
| Biochemistry, Genetics and Molecular Biology | 21 | 10% |
| Immunology and Microbiology | 8 | 4% |
| Nursing and Health Professions | 6 | 3% |
| Other | 19 | 9% |
| Unknown | 52 | 26% |