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Does a positive anti-CCP test identify a distinct arthritis entity?

Overview of attention for article published in Arthritis Research & Therapy, September 2005
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Title
Does a positive anti-CCP test identify a distinct arthritis entity?
Published in
Arthritis Research & Therapy, September 2005
DOI 10.1186/ar1836
Pubmed ID
Authors

Thomas Skogh

Abstract

The introduction of tests recognizing 'anti-citrullinated protein antibodies' (ACPA) has caused a revolution in rheumatology. Immunization against citrullinated proteins is a feature almost unique for rheumatoid arthritis, although ACPA may occur long before the onset of symptoms. Even if the presence of ACPA does not seem to reveal a distinct arthritis phenotype at symptom onset, it predicts an aggressive disease course with unfavourable outcome. Despite the very high diagnostic specificity for rheumatoid arthritis, ACPA-positivity does not always accord with a traditional diagnosis of rheumatoid arthritis at clinical presentation. However, even when these patients are judged to suffer from mild undifferentiated arthritis, they call for follow-up and special attention by rheumatologists.

Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 11 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Colombia 2 18%
United Kingdom 1 9%
Russia 1 9%
Unknown 7 64%

Demographic breakdown

Readers by professional status Count As %
Student > Postgraduate 3 27%
Student > Master 2 18%
Researcher 2 18%
Student > Ph. D. Student 1 9%
Lecturer 1 9%
Other 1 9%
Unknown 1 9%
Readers by discipline Count As %
Medicine and Dentistry 6 55%
Biochemistry, Genetics and Molecular Biology 2 18%
Immunology and Microbiology 1 9%
Agricultural and Biological Sciences 1 9%
Unknown 1 9%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 28 May 2012.
All research outputs
#22,758,309
of 25,373,627 outputs
Outputs from Arthritis Research & Therapy
#3,132
of 3,381 outputs
Outputs of similar age
#60,602
of 62,337 outputs
Outputs of similar age from Arthritis Research & Therapy
#10
of 11 outputs
Altmetric has tracked 25,373,627 research outputs across all sources so far. This one is in the 1st percentile – i.e., 1% of other outputs scored the same or lower than it.
So far Altmetric has tracked 3,381 research outputs from this source. They typically receive more attention than average, with a mean Attention Score of 9.2. This one is in the 1st percentile – i.e., 1% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 62,337 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 1st percentile – i.e., 1% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 11 others from the same source and published within six weeks on either side of this one. This one is in the 1st percentile – i.e., 1% of its contemporaries scored the same or lower than it.