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Anti-apoptotic gene transcription signature of salivary gland neoplasms

Overview of attention for article published in BMC Cancer, February 2012
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  • Above-average Attention Score compared to outputs of the same age and source (64th percentile)

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Title
Anti-apoptotic gene transcription signature of salivary gland neoplasms
Published in
BMC Cancer, February 2012
DOI 10.1186/1471-2407-12-61
Pubmed ID
Authors

Carolina Cavaliéri Gomes, Vanessa Fátima Bernardes, Marina Gonçalves Diniz, Luiz De Marco, Ricardo Santiago Gomez

Abstract

Development of accurate therapeutic approaches to salivary gland neoplasms depends on better understanding of their molecular pathogenesis. Tumour growth is regulated by the balance between proliferation and apoptosis. Few studies have investigated apoptosis in salivary tumours relying almost exclusively on immunohistochemistry or TUNEL assay. Furthermore, there is no information regarding the mRNA expression profile of apoptotic genes in salivary tumors. Our objective was to investigate the quantitative expression of BCL-2 (anti-apoptotic), BAX and Caspase3 (pro-apoptotic genes) mRNAs in salivary gland neoplasms and examine the association of these data with tumour size, proliferative activity and p53 staining (parameters associated with a poor prognosis of salivary tumours patients).

X Demographics

X Demographics

The data shown below were collected from the profiles of 3 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 20 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Brazil 1 5%
Unknown 19 95%

Demographic breakdown

Readers by professional status Count As %
Researcher 5 25%
Student > Bachelor 2 10%
Student > Ph. D. Student 2 10%
Professor 1 5%
Student > Master 1 5%
Other 3 15%
Unknown 6 30%
Readers by discipline Count As %
Medicine and Dentistry 9 45%
Agricultural and Biological Sciences 2 10%
Neuroscience 1 5%
Biochemistry, Genetics and Molecular Biology 1 5%
Unknown 7 35%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 3. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 28 June 2012.
All research outputs
#12,565,593
of 22,668,244 outputs
Outputs from BMC Cancer
#2,600
of 8,243 outputs
Outputs of similar age
#140,260
of 247,607 outputs
Outputs of similar age from BMC Cancer
#27
of 75 outputs
Altmetric has tracked 22,668,244 research outputs across all sources so far. This one is in the 44th percentile – i.e., 44% of other outputs scored the same or lower than it.
So far Altmetric has tracked 8,243 research outputs from this source. They receive a mean Attention Score of 4.3. This one has gotten more attention than average, scoring higher than 68% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 247,607 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 43rd percentile – i.e., 43% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 75 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 64% of its contemporaries.